Reactome | NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP

Schema > Reaction > Entries

NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP Show undefined attributes

catalystActivity	[CatalystActivity:10641352] hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides of NUDT1 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10641354
displayName	NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP
eventOf	[Pathway:R-DRE-2393930] Phosphate bond hydrolysis by NUDT proteins - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DRE-71732] PPA1 hydrolyzes pyrophosphate to orthophosphate - Danio rerio
inferredFrom	[Reaction:R-HSA-9731590] NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP - Homo sapiens
input	[SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-9731603] O(6)-methyl-dGTP(4-) [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP O(6)-methyl-dGTP + H2O => O(6)-methyl-dGMP + diphosphate + H(+)
output	[SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-9731591] O(6)-methyl-dGMP(2-) [cytosol] [SimpleEntity:R-ALL-111294] PPi [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-9731590
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(precedingEvent)	[Reaction:R-DRE-71732] PPA1 hydrolyzes pyrophosphate to orthophosphate
(hasEvent)	[Pathway:R-DRE-2393930] Phosphate bond hydrolysis by NUDT proteins
(inferredTo)	[Reaction:R-HSA-9731590] NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP

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