Reactome | Phosphate bond hydrolysis by NUDT proteins

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Phosphate bond hydrolysis by NUDT proteins Show undefined attributes

created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10649696
displayName	Phosphate bond hydrolysis by NUDT proteins
eventOf	[Pathway:R-DRE-74259] Purine catabolism - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:258153] nucleobase-containing small molecule metabolic process
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-DRE-2395849] NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP - Danio rerio [Reaction:R-DRE-2395869] NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP - Danio rerio [Reaction:R-DRE-2395876] NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP - Danio rerio [Reaction:R-DRE-2395879] NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP - Danio rerio [Reaction:R-DRE-2395873] NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP - Danio rerio [Reaction:R-DRE-2395965] NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP - Danio rerio [Reaction:R-DRE-2395818] NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP - Danio rerio [Reaction:R-DRE-2395872] NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP - Danio rerio [Reaction:R-DRE-9731228] NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP - Danio rerio [Reaction:R-DRE-9731632] NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP - Danio rerio [Reaction:R-DRE-9731613] NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP - Danio rerio [Reaction:R-DRE-9731590] NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP - Danio rerio [Reaction:R-DRE-2509793] NUDT16 hydrolyses dIDP to dIMP - Danio rerio [Reaction:R-DRE-2509816] NUDT16 hydrolyses IDP to IMP - Danio rerio [Reaction:R-DRE-2393939] Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP - Danio rerio [Reaction:R-DRE-2393954] Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP - Danio rerio [Reaction:R-DRE-5696049] ADPRM hydrolyses ADP-ribose to R5P and AMP - Danio rerio
inferredFrom	[Pathway:R-HSA-2393930] Phosphate bond hydrolysis by NUDT proteins - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Phosphate bond hydrolysis by NUDT proteins
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68323] Danio rerio
stId	R-DRE-2393930
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-74259] Purine catabolism
(inferredTo)	[Pathway:R-HSA-2393930] Phosphate bond hydrolysis by NUDT proteins

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