Reactome | activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10616175
displayName	activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane]
hasComponent	[Complex:R-DRE-5672723] activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] [CandidateSet:R-ALL-9657574] single mechanism MAP2K1/2 inhibitors [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-9657587] activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] - Homo sapiens
maxDepth	12
name	activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors
negativelyRegulates	[NegativeRegulation:10616194] Negative regulation by 'activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane]'
producedByEvent	[Reaction:R-DRE-9657606] Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks - Danio rerio
schemaClass	Complex
species	[Species:68323] Danio rerio
stId	R-DRE-9657587
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(output)	[Reaction:R-DRE-9657606] Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks
(regulator)	[NegativeRegulation:10616194] Negative regulation by 'activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane]'
(inferredTo)	[Complex:R-HSA-9657587] activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane]

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