Reactome | TRAF6 mediated IRF7 activation

Schema > Pathway > Entries

compartment	[Compartment:17906] mitochondrial outer membrane
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10649306
displayName	TRAF6 mediated IRF7 activation
eventOf	[Pathway:R-DRE-168928] DDX58/IFIH1-mediated induction of interferon-alpha/beta - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-DRE-933533] Dimerization of p-IRF7 - Danio rerio [Reaction:R-DRE-933531] Translocation of p-IRF7:p-IRF7 to nucleus - Danio rerio
inferredFrom	[Pathway:R-HSA-933541] TRAF6 mediated IRF7 activation - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	TRAF6 mediated IRF7 activation
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68323] Danio rerio
stId	R-DRE-933541
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DRE-168928] DDX58/IFIH1-mediated induction of interferon-alpha/beta
(inferredTo)	[Pathway:R-HSA-933541] TRAF6 mediated IRF7 activation

Cite Us!