Reactome | Translocation of p-IRF7:p-IRF7 to nucleus

Schema > Reaction > Entries

category	transition
compartment	[Compartment:13231] nuclear envelope
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10590316
displayName	Translocation of p-IRF7:p-IRF7 to nucleus
eventOf	[Pathway:R-DRE-975110] TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-933531] Translocation of p-IRF7:p-IRF7 to nucleus - Homo sapiens
input	[Complex:R-DRE-450344] p-2S-IRF7:p-2S-IRF7 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Translocation of p-IRF7:p-IRF7 to nucleus
output	[Complex:R-DRE-450306] 2xp-S477,S479-IRF7 [nucleoplasm]
precedingEvent	[Reaction:R-DRE-933533] Dimerization of p-IRF7 - Danio rerio
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-933531
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DRE-975110] TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling [Pathway:R-DRE-933541] TRAF6 mediated IRF7 activation
(inferredTo)	[Reaction:R-HSA-933531] Translocation of p-IRF7:p-IRF7 to nucleus

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