Reactome | ube2ia [nucleoplasm]

Schema > EntityWithAccessionedSequence > Entries

ube2ia [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[Reaction:R-DRE-4085350] SUMOylation of UBE2I with SUMO1 - Danio rerio [Reaction:R-DRE-2993780] Transfer of SUMO1 from E1 to UBE2I (UBC9) - Danio rerio
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10605064
displayName	ube2ia [nucleoplasm]
endCoordinate	158
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-912481] UBE2I [nucleoplasm] - Homo sapiens
maxDepth	1
name	ube2ia UBE2I Q9W6H5
producedByEvent	[Reaction:R-DRE-4085350] SUMOylation of UBE2I with SUMO1 - Danio rerio [Reaction:R-DRE-3968362] SUMOylation of PIAS4 with SUMO1 - Danio rerio [Reaction:R-DRE-3000434] PML, TRIM27, PIAS1,2-1 SUMOylate MDM2 with SUMO1 - Danio rerio [Reaction:R-DRE-4551721] PIAS4 SUMOylates VHL with SUMO1 - Danio rerio [Reaction:R-DRE-4551721] PIAS4 SUMOylates VHL with SUMO1 - Danio rerio [Reaction:R-DRE-4551721] PIAS4 SUMOylates VHL with SUMO1 - Danio rerio [Reaction:R-DRE-5228523] RANBP2 SUMOylates MDM2 with SUMO1 - Danio rerio [Reaction:R-DRE-4086083] SUMOylation of ING2 with SUMO1 - Danio rerio [Reaction:R-DRE-4086088] SUMOylation of NPM1 with SUMO1 - Danio rerio [Reaction:R-DRE-3900047] SUMOylation of DDX17 with SUMO1 - Danio rerio [Reaction:R-DRE-3927824] PRC1 SUMOylates CASP8AP2 with SUMO1 - Danio rerio [Reaction:R-DRE-4086036] PIAS1,3 SUMOylate NRIP1 with SUMO1 - Danio rerio [Reaction:R-DRE-4086036] PIAS1,3 SUMOylate NRIP1 with SUMO1 - Danio rerio [Reaction:R-DRE-3900177] SUMOylation of DDX5 with SUMO1 - Danio rerio [Reaction:R-DRE-5228521] PIAS1,4 SUMOylate CASP8AP2 with SUMO1 - Danio rerio [Reaction:R-DRE-3108209] PRC1 SUMOylates CTBP1 with SUMO1 - Danio rerio [Reaction:R-DRE-4085347] PIAS1 SUMOylates SAFB with SUMO1 - Danio rerio [Reaction:R-DRE-4085347] PIAS1 SUMOylates SAFB with SUMO1 - Danio rerio [Reaction:R-DRE-3900070] SUMOylation of MKL1 with SUMO1 - Danio rerio [Reaction:R-DRE-3900070] SUMOylation of MKL1 with SUMO1 - Danio rerio [Reaction:R-DRE-3900070] SUMOylation of MKL1 with SUMO1 - Danio rerio [Reaction:R-DRE-4090284] SUMOylation of HIPK2 with SUMO1 - Danio rerio [Reaction:R-DRE-4085296] SUMOylation of NCOA1 with SUMO1 - Danio rerio [Reaction:R-DRE-4085296] SUMOylation of NCOA1 with SUMO1 - Danio rerio [Reaction:R-DRE-4090288] PIAS1,3 SUMOylate MBD1 with SUMO1 - Danio rerio [Reaction:R-DRE-4090288] PIAS1,3 SUMOylate MBD1 with SUMO1 - Danio rerio [Reaction:R-DRE-3296126] CBX4, UHRF2 SUMOylate ZNF131 with SUMO1 - Danio rerio [Reaction:R-DRE-4641342] SUMOylation of TOP2A with SUMO1 - Danio rerio [Reaction:R-DRE-4641345] SUMOylation of TOP2B with SUMO1 - Danio rerio [Reaction:R-DRE-4641362] SUMOylation of TOP1 with SUMO1 - Danio rerio [Reaction:R-DRE-4615910] SUMOylation of PCNA with SUMO1 - Danio rerio [Reaction:R-DRE-4615910] SUMOylation of PCNA with SUMO1 - Danio rerio [Reaction:R-DRE-4615910] SUMOylation of PCNA with SUMO1 - Danio rerio [Reaction:R-DRE-4570554] SUMOylation of MDC1 with SUMO1 - Danio rerio [Reaction:R-DRE-4568863] SUMOylation of RAD52 with SUMO1 - Danio rerio [Reaction:R-DRE-4568863] SUMOylation of RAD52 with SUMO1 - Danio rerio [Reaction:R-DRE-4568863] SUMOylation of RAD52 with SUMO1 - Danio rerio [Reaction:R-DRE-4568848] PIAS1,2-1 SUMOylates XRCC4 with SUMO1 - Danio rerio [Reaction:R-DRE-4551604] PIAS4 SUMOylates PARP1 with SUMO1 - Danio rerio [Reaction:R-DRE-4551604] PIAS4 SUMOylates PARP1 with SUMO1 - Danio rerio [Reaction:R-DRE-4551661] PIAS4 SUMOylates RNF168 with SUMO1 - Danio rerio [Reaction:R-DRE-4570528] SUMOylation of XPC with SUMO1 - Danio rerio [Reaction:R-DRE-4551648] SUMOylation of TDG with SUMO1 - Danio rerio [Reaction:R-DRE-3000399] RANBP2 SUMOylates SP100 with SUMO1 - Danio rerio [Reaction:R-DRE-4341048] SUMOylation of RXRA with SUMO1 - Danio rerio [Reaction:R-DRE-4090390] PIAS1,2-1 SUMOylates AR with SUMO1 - Danio rerio [Reaction:R-DRE-4090390] PIAS1,2-1 SUMOylates AR with SUMO1 - Danio rerio [Reaction:R-DRE-5682607] PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs - Danio rerio [Reaction:R-DRE-5684052] PIAS4 SUMOylates MDC1 - Danio rerio [Reaction:R-DRE-5684052] PIAS4 SUMOylates MDC1 - Danio rerio [Reaction:R-DRE-5684052] PIAS4 SUMOylates MDC1 - Danio rerio [Reaction:R-DRE-5684052] PIAS4 SUMOylates MDC1 - Danio rerio [Reaction:R-DRE-6790454] SUMOylation of XPC - Danio rerio [Reaction:R-DRE-4755411] PIAS4 SUMOylates IKBKG with SUMO1 - Danio rerio [Reaction:R-DRE-4755411] PIAS4 SUMOylates IKBKG with SUMO1 - Danio rerio [Reaction:R-DRE-4656914] SUMOylation of NFKBIA with SUMO1 - Danio rerio [Reaction:R-DRE-3234094] SUMOylation of TFAP2C with SUMO1 - Danio rerio [Reaction:R-DRE-3234094] SUMOylation of TFAP2C with SUMO1 - Danio rerio [Reaction:R-DRE-9940470] GATAD2A is SUMOylated - Danio rerio [Reaction:R-DRE-9940470] GATAD2A is SUMOylated - Danio rerio [Reaction:R-DRE-9926476] UBE2I sumoylates MITF-M - Danio rerio [Reaction:R-DRE-9926476] UBE2I sumoylates MITF-M - Danio rerio [Reaction:R-DRE-4570496] SUMOylation of Histone H4 with SUMO1 - Danio rerio [Reaction:R-DRE-4615872] RANBP2 SUMOylates HDAC4 with SUMO1 - Danio rerio [Reaction:R-DRE-4615905] PIAS1 SUMOylates SATB1 with SUMO1 - Danio rerio [Reaction:R-DRE-4616015] SUMOylation of HDAC2 with SUMO1 - Danio rerio [Reaction:R-DRE-4615889] SUMOylation of HDAC1 with SUMO1 - Danio rerio [Reaction:R-DRE-4615889] SUMOylation of HDAC1 with SUMO1 - Danio rerio [Reaction:R-DRE-4655374] SUMOylation of DNMT3B with SUMO1 - Danio rerio [Reaction:R-DRE-4570467] SUMOylation of NOP58 with SUMO1 - Danio rerio [Reaction:R-DRE-4570467] SUMOylation of NOP58 with SUMO1 - Danio rerio [Reaction:R-DRE-3968414] UBE2I (UBC9), PIAS1 SUMOylate FOXL2 with SUMO1 - Danio rerio [Reaction:R-DRE-3968414] UBE2I (UBC9), PIAS1 SUMOylate FOXL2 with SUMO1 - Danio rerio [Reaction:R-DRE-3968414] UBE2I (UBC9), PIAS1 SUMOylate FOXL2 with SUMO1 - Danio rerio [Reaction:R-DRE-3232162] PIAS3 SUMOylates MITF with SUMO1 - Danio rerio [Reaction:R-DRE-3232162] PIAS3 SUMOylates MITF with SUMO1 - Danio rerio [Reaction:R-DRE-6804468] PIAS1 SUMOylates SP3 with SUMO2 - Danio rerio [Reaction:R-DRE-6804468] PIAS1 SUMOylates SP3 with SUMO2 - Danio rerio [Reaction:R-DRE-3247493] PIAS1 SUMOylates SP3 with SUMO1 - Danio rerio [Reaction:R-DRE-4090281] PIAS1,2-1 SUMOylate HIC1 with SUMO1 - Danio rerio [Reaction:R-DRE-3465545] PIAS1,3,4 SUMOylate MTA1 with SUMO2,3 - Danio rerio [Reaction:R-DRE-3465545] PIAS1,3,4 SUMOylate MTA1 with SUMO2,3 - Danio rerio [Reaction:R-DRE-4719436] PIAS2,3,4 SUMOylate RORA with SUMO1 - Danio rerio [Reaction:R-DRE-4719424] PIAS1 SUMOylates THRB with SUMO1 - Danio rerio [Reaction:R-DRE-4719424] PIAS1 SUMOylates THRB with SUMO1 - Danio rerio [Reaction:R-DRE-4719424] PIAS1 SUMOylates THRB with SUMO1 - Danio rerio [Reaction:R-DRE-4341070] PIAS4 SUMOylates PPARA with SUMO1 - Danio rerio [Reaction:R-DRE-4341073] PIAS3 SUMOylates PGR with SUMO1 - Danio rerio [Reaction:R-DRE-4341073] PIAS3 SUMOylates PGR with SUMO1 - Danio rerio [Reaction:R-DRE-4341073] PIAS3 SUMOylates PGR with SUMO1 - Danio rerio [Reaction:R-DRE-4090408] PIAS1,3 SUMOylate ESR1 with SUMO1 - Danio rerio [Reaction:R-DRE-4090408] PIAS1,3 SUMOylate ESR1 with SUMO1 - Danio rerio [Reaction:R-DRE-4090408] PIAS1,3 SUMOylate ESR1 with SUMO1 - Danio rerio [Reaction:R-DRE-4090408] PIAS1,3 SUMOylate ESR1 with SUMO1 - Danio rerio [Reaction:R-DRE-4090408] PIAS1,3 SUMOylate ESR1 with SUMO1 - Danio rerio [Reaction:R-DRE-4546386] PIAS1,3 SUMOylates NR5A1 with SUMO1 - Danio rerio [Reaction:R-DRE-4546386] PIAS1,3 SUMOylates NR5A1 with SUMO1 - Danio rerio [Reaction:R-DRE-4341016] PIAS1 SUMOylates NR3C2 (Mineralcorticoid Receptor) with SUMO1 - Danio rerio [Reaction:R-DRE-4341016] PIAS1 SUMOylates NR3C2 (Mineralcorticoid Receptor) with SUMO1 - Danio rerio [Reaction:R-DRE-4341016] PIAS1 SUMOylates NR3C2 (Mineralcorticoid Receptor) with SUMO1 - Danio rerio [Reaction:R-DRE-4341016] PIAS1 SUMOylates NR3C2 (Mineralcorticoid Receptor) with SUMO1 - Danio rerio [Reaction:R-DRE-3782535] TRIM28 SUMOylates TRIM28:ZNF350 with SUMO1 - Danio rerio [Reaction:R-DRE-3782535] TRIM28 SUMOylates TRIM28:ZNF350 with SUMO1 - Danio rerio [Reaction:R-DRE-3782535] TRIM28 SUMOylates TRIM28:ZNF350 with SUMO1 - Danio rerio [Reaction:R-DRE-3782535] TRIM28 SUMOylates TRIM28:ZNF350 with SUMO1 - Danio rerio [Reaction:R-DRE-3782535] TRIM28 SUMOylates TRIM28:ZNF350 with SUMO1 - Danio rerio [Reaction:R-DRE-3782535] TRIM28 SUMOylates TRIM28:ZNF350 with SUMO1 - Danio rerio [Reaction:R-DRE-3900194] PIAS1 SUMOylates DDX5 with SUMO2 - Danio rerio [Reaction:R-DRE-3900194] PIAS1 SUMOylates DDX5 with SUMO2 - Danio rerio [Reaction:R-DRE-4086059] SUMOylation of NPM1 with SUMO2,3 - Danio rerio [Reaction:R-DRE-4086059] SUMOylation of NPM1 with SUMO2,3 - Danio rerio [Reaction:R-DRE-3108203] PRC1 SUMOylates CTBP1 with SUMO2,3 - Danio rerio [Reaction:R-DRE-3108203] PRC1 SUMOylates CTBP1 with SUMO2,3 - Danio rerio [Reaction:R-DRE-4085372] PIAS1 SUMOylates SAFB with SUMO2,3 - Danio rerio [Reaction:R-DRE-4085372] PIAS1 SUMOylates SAFB with SUMO2,3 - Danio rerio [Reaction:R-DRE-4085372] PIAS1 SUMOylates SAFB with SUMO2,3 - Danio rerio [Reaction:R-DRE-4085372] PIAS1 SUMOylates SAFB with SUMO2,3 - Danio rerio [Reaction:R-DRE-4641350] PIAS4 SUMOylates TOP2A with SUMO2,3 - Danio rerio [Reaction:R-DRE-4641350] PIAS4 SUMOylates TOP2A with SUMO2,3 - Danio rerio [Reaction:R-DRE-4551738] SUMOylation of TDG with SUMO2,3 - Danio rerio [Reaction:R-DRE-4551738] SUMOylation of TDG with SUMO2,3 - Danio rerio [Reaction:R-DRE-4551768] PIAS4 SUMOylates PARP1 with SUMO2,3 - Danio rerio [Reaction:R-DRE-4551768] PIAS4 SUMOylates PARP1 with SUMO2,3 - Danio rerio [Reaction:R-DRE-4551768] PIAS4 SUMOylates PARP1 with SUMO2,3 - Danio rerio [Reaction:R-DRE-4551768] PIAS4 SUMOylates PARP1 with SUMO2,3 - Danio rerio [Reaction:R-DRE-4570553] SUMOylation of MDC1 with SUMO2,3 - Danio rerio [Reaction:R-DRE-4570553] SUMOylation of MDC1 with SUMO2,3 - Danio rerio [Reaction:R-DRE-3108212] SMC5-SMC6 Complex SUMOylates Cohesin with SUMO1 - Danio rerio [Reaction:R-DRE-3108212] SMC5-SMC6 Complex SUMOylates Cohesin with SUMO1 - Danio rerio [Reaction:R-DRE-4570463] CBX4 (Pc2) SUMOylates CETN2 with SUMO2,3 - Danio rerio [Reaction:R-DRE-4570463] CBX4 (Pc2) SUMOylates CETN2 with SUMO2,3 - Danio rerio [Reaction:R-DRE-3000348] RANBP2 SUMOylates SP100 with SUMO2 - Danio rerio [Reaction:R-DRE-3000348] RANBP2 SUMOylates SP100 with SUMO2 - Danio rerio [Reaction:R-DRE-4551616] SUMOylation of RPA1 (RPA70) with SUMO2,3 - Danio rerio [Reaction:R-DRE-4551616] SUMOylation of RPA1 (RPA70) with SUMO2,3 - Danio rerio [Reaction:R-DRE-4551616] SUMOylation of RPA1 (RPA70) with SUMO2,3 - Danio rerio [Reaction:R-DRE-4551616] SUMOylation of RPA1 (RPA70) with SUMO2,3 - Danio rerio [Reaction:R-DRE-4719413] PIAS2,3,4 SUMOylate RORA with SUMO2 - Danio rerio [Reaction:R-DRE-4719413] PIAS2,3,4 SUMOylate RORA with SUMO2 - Danio rerio [Reaction:R-DRE-4720432] HDAC4 SUMOylates NR1H2 (LXRbeta) with SUMO2,3 - Danio rerio [Reaction:R-DRE-4720432] HDAC4 SUMOylates NR1H2 (LXRbeta) with SUMO2,3 - Danio rerio [Reaction:R-DRE-4720432] HDAC4 SUMOylates NR1H2 (LXRbeta) with SUMO2,3 - Danio rerio [Reaction:R-DRE-4720432] HDAC4 SUMOylates NR1H2 (LXRbeta) with SUMO2,3 - Danio rerio [Reaction:R-DRE-4720446] HDAC4 SUMOylates NR1H3 (LXRalpha) with SUMO2,3 - Danio rerio [Reaction:R-DRE-4720446] HDAC4 SUMOylates NR1H3 (LXRalpha) with SUMO2,3 - Danio rerio [Reaction:R-DRE-4755494] PIAS1,2-1 SUMOylate NR5A2 with SUMO1 - Danio rerio [Reaction:R-DRE-3000449] UBC9 (UBE2I) SUMOylates RANGAP1 with SUMO, which targets RANGAP1 to RANBP2 - Danio rerio [Reaction:R-DRE-3000449] UBC9 (UBE2I) SUMOylates RANGAP1 with SUMO, which targets RANGAP1 to RANBP2 - Danio rerio [Reaction:R-DRE-4546387] PIAS4 SUMOylates VDR with SUMO2 - Danio rerio [Reaction:R-DRE-4546387] PIAS4 SUMOylates VDR with SUMO2 - Danio rerio [Reaction:R-DRE-6804485] PIAS1 SUMOylates L3MBTL2 with SUMO2 - Danio rerio [Reaction:R-DRE-6804485] PIAS1 SUMOylates L3MBTL2 with SUMO2 - Danio rerio [Reaction:R-DRE-6804485] PIAS1 SUMOylates L3MBTL2 with SUMO2 - Danio rerio [Reaction:R-DRE-6804485] PIAS1 SUMOylates L3MBTL2 with SUMO2 - Danio rerio [Reaction:R-DRE-4570485] SUMOylation of Histone H4 with SUMO3 - Danio rerio [Reaction:R-DRE-4570485] SUMOylation of Histone H4 with SUMO3 - Danio rerio [Reaction:R-DRE-4615987] RANBP2 SUMOylates HDAC4 with SUMO2,3 - Danio rerio [Reaction:R-DRE-4615987] RANBP2 SUMOylates HDAC4 with SUMO2,3 - Danio rerio [Reaction:R-DRE-4615839] PIAS1 SUMOylates SATB1 with SUMO2,3 - Danio rerio [Reaction:R-DRE-4615839] PIAS1 SUMOylates SATB1 with SUMO2,3 - Danio rerio [Reaction:R-DRE-4570499] CBX4 (Pc2) SUMOylates HNRNPK with SUMO2 - Danio rerio [Reaction:R-DRE-4570499] CBX4 (Pc2) SUMOylates HNRNPK with SUMO2 - Danio rerio [Reaction:R-DRE-4570489] SUMOylation of NOP58 with SUMO2 - Danio rerio [Reaction:R-DRE-4570489] SUMOylation of NOP58 with SUMO2 - Danio rerio [Reaction:R-DRE-4570489] SUMOylation of NOP58 with SUMO2 - Danio rerio [Reaction:R-DRE-4570489] SUMOylation of NOP58 with SUMO2 - Danio rerio [BlackBoxEvent:R-DRE-4755524] SUMOylation of NR1I2 with SUMO3 - Danio rerio [BlackBoxEvent:R-DRE-4755524] SUMOylation of NR1I2 with SUMO3 - Danio rerio [Reaction:R-DRE-4719448] PIAS1 SUMOylates THRB with SUMO3 - Danio rerio [Reaction:R-DRE-4719448] PIAS1 SUMOylates THRB with SUMO3 - Danio rerio [Reaction:R-DRE-4719448] PIAS1 SUMOylates THRB with SUMO3 - Danio rerio [Reaction:R-DRE-4719448] PIAS1 SUMOylates THRB with SUMO3 - Danio rerio [Reaction:R-DRE-4719448] PIAS1 SUMOylates THRB with SUMO3 - Danio rerio [Reaction:R-DRE-4719448] PIAS1 SUMOylates THRB with SUMO3 - Danio rerio [Reaction:R-DRE-4341072] SUMOylation of RARA with SUMO2 - Danio rerio [Reaction:R-DRE-4341072] SUMOylation of RARA with SUMO2 - Danio rerio [Reaction:R-DRE-4341072] SUMOylation of RARA with SUMO2 - Danio rerio [Reaction:R-DRE-4341072] SUMOylation of RARA with SUMO2 - Danio rerio [Reaction:R-DRE-4341072] SUMOylation of RARA with SUMO2 - Danio rerio [Reaction:R-DRE-4341072] SUMOylation of RARA with SUMO2 - Danio rerio [BlackBoxEvent:R-DRE-4755419] SUMOylation of NR1H4 with SUMO1 - Danio rerio [BlackBoxEvent:R-DRE-4755419] SUMOylation of NR1H4 with SUMO1 - Danio rerio [Reaction:R-DRE-4546385] PIAS1,3 SUMOylates NR5A1 with SUMO2 - Danio rerio [Reaction:R-DRE-4546385] PIAS1,3 SUMOylates NR5A1 with SUMO2 - Danio rerio [Reaction:R-DRE-4546385] PIAS1,3 SUMOylates NR5A1 with SUMO2 - Danio rerio [Reaction:R-DRE-4546385] PIAS1,3 SUMOylates NR5A1 with SUMO2 - Danio rerio [Reaction:R-DRE-4341025] SUMOylation of NR3C1 (GR) with SUMO1 - Danio rerio [Reaction:R-DRE-4341025] SUMOylation of NR3C1 (GR) with SUMO1 - Danio rerio [Reaction:R-DRE-4341025] SUMOylation of NR3C1 (GR) with SUMO1 - Danio rerio [Reaction:R-DRE-4341025] SUMOylation of NR3C1 (GR) with SUMO1 - Danio rerio
referenceEntity	[ReferenceGeneProduct:uniprot:Q9W6H5] UniProt:Q9W6H5
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:68323] Danio rerio
stId	R-DRE-912481
startCoordinate	1

Referrals

(input)	[Reaction:R-DRE-4085350] SUMOylation of UBE2I with SUMO1 [Reaction:R-DRE-2993780] Transfer of SUMO1 from E1 to UBE2I (UBC9)
(output)	[Reaction:R-DRE-4085350] SUMOylation of UBE2I with SUMO1 [Reaction:R-DRE-3968362] SUMOylation of PIAS4 with SUMO1 [Reaction:R-DRE-3000434] PML, TRIM27, PIAS1,2-1 SUMOylate MDM2 with SUMO1 [Reaction:R-DRE-4551721] PIAS4 SUMOylates VHL with SUMO1 [Reaction:R-DRE-5228523] RANBP2 SUMOylates MDM2 with SUMO1 [Reaction:R-DRE-3782535] TRIM28 SUMOylates TRIM28:ZNF350 with SUMO1 [Reaction:R-DRE-4086083] SUMOylation of ING2 with SUMO1 [Reaction:R-DRE-4086088] SUMOylation of NPM1 with SUMO1 [Reaction:R-DRE-3900047] SUMOylation of DDX17 with SUMO1 [Reaction:R-DRE-3927824] PRC1 SUMOylates CASP8AP2 with SUMO1 [Reaction:R-DRE-4086036] PIAS1,3 SUMOylate NRIP1 with SUMO1 [Reaction:R-DRE-3900177] SUMOylation of DDX5 with SUMO1 [Reaction:R-DRE-5228521] PIAS1,4 SUMOylate CASP8AP2 with SUMO1 [Reaction:R-DRE-3108209] PRC1 SUMOylates CTBP1 with SUMO1 [Reaction:R-DRE-4085347] PIAS1 SUMOylates SAFB with SUMO1 [Reaction:R-DRE-3900070] SUMOylation of MKL1 with SUMO1 [Reaction:R-DRE-3900194] PIAS1 SUMOylates DDX5 with SUMO2 [Reaction:R-DRE-4086059] SUMOylation of NPM1 with SUMO2,3 [Reaction:R-DRE-4090284] SUMOylation of HIPK2 with SUMO1 [Reaction:R-DRE-4085296] SUMOylation of NCOA1 with SUMO1 [Reaction:R-DRE-4090288] PIAS1,3 SUMOylate MBD1 with SUMO1 [Reaction:R-DRE-3296126] CBX4, UHRF2 SUMOylate ZNF131 with SUMO1 [Reaction:R-DRE-3108203] PRC1 SUMOylates CTBP1 with SUMO2,3 [Reaction:R-DRE-4085372] PIAS1 SUMOylates SAFB with SUMO2,3 [Reaction:R-DRE-4641342] SUMOylation of TOP2A with SUMO1 [Reaction:R-DRE-4641345] SUMOylation of TOP2B with SUMO1 [Reaction:R-DRE-4641362] SUMOylation of TOP1 with SUMO1 [Reaction:R-DRE-4641350] PIAS4 SUMOylates TOP2A with SUMO2,3 [Reaction:R-DRE-4615910] SUMOylation of PCNA with SUMO1 [Reaction:R-DRE-4551738] SUMOylation of TDG with SUMO2,3 [Reaction:R-DRE-4570554] SUMOylation of MDC1 with SUMO1 [Reaction:R-DRE-4551768] PIAS4 SUMOylates PARP1 with SUMO2,3 [Reaction:R-DRE-4570553] SUMOylation of MDC1 with SUMO2,3 [Reaction:R-DRE-3108212] SMC5-SMC6 Complex SUMOylates Cohesin with SUMO1 [Reaction:R-DRE-4568863] SUMOylation of RAD52 with SUMO1 [Reaction:R-DRE-4570463] CBX4 (Pc2) SUMOylates CETN2 with SUMO2,3 [Reaction:R-DRE-4568848] PIAS1,2-1 SUMOylates XRCC4 with SUMO1 [Reaction:R-DRE-3000348] RANBP2 SUMOylates SP100 with SUMO2 [Reaction:R-DRE-4551604] PIAS4 SUMOylates PARP1 with SUMO1 [Reaction:R-DRE-4551661] PIAS4 SUMOylates RNF168 with SUMO1 [Reaction:R-DRE-4570528] SUMOylation of XPC with SUMO1 [Reaction:R-DRE-4551648] SUMOylation of TDG with SUMO1 [Reaction:R-DRE-4551616] SUMOylation of RPA1 (RPA70) with SUMO2,3 [Reaction:R-DRE-3000399] RANBP2 SUMOylates SP100 with SUMO1 [Reaction:R-DRE-4719413] PIAS2,3,4 SUMOylate RORA with SUMO2 [Reaction:R-DRE-4341048] SUMOylation of RXRA with SUMO1 [Reaction:R-DRE-4720432] HDAC4 SUMOylates NR1H2 (LXRbeta) with SUMO2,3 [Reaction:R-DRE-4720446] HDAC4 SUMOylates NR1H3 (LXRalpha) with SUMO2,3 [Reaction:R-DRE-4755494] PIAS1,2-1 SUMOylate NR5A2 with SUMO1 [Reaction:R-DRE-4090390] PIAS1,2-1 SUMOylates AR with SUMO1 [Reaction:R-DRE-5682607] PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs [Reaction:R-DRE-5684052] PIAS4 SUMOylates MDC1 [Reaction:R-DRE-3000449] UBC9 (UBE2I) SUMOylates RANGAP1 with SUMO, which targets RANGAP1 to RANBP2 [Reaction:R-DRE-6790454] SUMOylation of XPC [Reaction:R-DRE-4755411] PIAS4 SUMOylates IKBKG with SUMO1 [Reaction:R-DRE-4656914] SUMOylation of NFKBIA with SUMO1 [Reaction:R-DRE-4546387] PIAS4 SUMOylates VDR with SUMO2 [Reaction:R-DRE-3234094] SUMOylation of TFAP2C with SUMO1 [Reaction:R-DRE-9940470] GATAD2A is SUMOylated [Reaction:R-DRE-9926476] UBE2I sumoylates MITF-M [Reaction:R-DRE-6804485] PIAS1 SUMOylates L3MBTL2 with SUMO2 [Reaction:R-DRE-4570496] SUMOylation of Histone H4 with SUMO1 [Reaction:R-DRE-4615872] RANBP2 SUMOylates HDAC4 with SUMO1 [Reaction:R-DRE-4615905] PIAS1 SUMOylates SATB1 with SUMO1 [Reaction:R-DRE-4616015] SUMOylation of HDAC2 with SUMO1 [Reaction:R-DRE-4570485] SUMOylation of Histone H4 with SUMO3 [Reaction:R-DRE-4615987] RANBP2 SUMOylates HDAC4 with SUMO2,3 [Reaction:R-DRE-4615889] SUMOylation of HDAC1 with SUMO1 [Reaction:R-DRE-4615839] PIAS1 SUMOylates SATB1 with SUMO2,3 [Reaction:R-DRE-4655374] SUMOylation of DNMT3B with SUMO1 [Reaction:R-DRE-4570499] CBX4 (Pc2) SUMOylates HNRNPK with SUMO2 [Reaction:R-DRE-4570467] SUMOylation of NOP58 with SUMO1 [Reaction:R-DRE-4570489] SUMOylation of NOP58 with SUMO2 [Reaction:R-DRE-3968414] UBE2I (UBC9), PIAS1 SUMOylate FOXL2 with SUMO1 [Reaction:R-DRE-3232162] PIAS3 SUMOylates MITF with SUMO1 [Reaction:R-DRE-6804468] PIAS1 SUMOylates SP3 with SUMO2 [Reaction:R-DRE-3247493] PIAS1 SUMOylates SP3 with SUMO1 [Reaction:R-DRE-4090281] PIAS1,2-1 SUMOylate HIC1 with SUMO1 [Reaction:R-DRE-3465545] PIAS1,3,4 SUMOylate MTA1 with SUMO2,3 [Reaction:R-DRE-4719436] PIAS2,3,4 SUMOylate RORA with SUMO1 [Reaction:R-DRE-4719424] PIAS1 SUMOylates THRB with SUMO1 [BlackBoxEvent:R-DRE-4755524] SUMOylation of NR1I2 with SUMO3 [Reaction:R-DRE-4341070] PIAS4 SUMOylates PPARA with SUMO1 [Reaction:R-DRE-4719448] PIAS1 SUMOylates THRB with SUMO3 [Reaction:R-DRE-4341072] SUMOylation of RARA with SUMO2 [BlackBoxEvent:R-DRE-4755419] SUMOylation of NR1H4 with SUMO1 [Reaction:R-DRE-4341073] PIAS3 SUMOylates PGR with SUMO1 [Reaction:R-DRE-4546385] PIAS1,3 SUMOylates NR5A1 with SUMO2 [Reaction:R-DRE-4090408] PIAS1,3 SUMOylate ESR1 with SUMO1 [Reaction:R-DRE-4546386] PIAS1,3 SUMOylates NR5A1 with SUMO1 [Reaction:R-DRE-4341016] PIAS1 SUMOylates NR3C2 (Mineralcorticoid Receptor) with SUMO1 [Reaction:R-DRE-4341025] SUMOylation of NR3C1 (GR) with SUMO1
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-912481] UBE2I [nucleoplasm]
(activeUnit)	[CatalystActivity:10608597] SUMO transferase activity of UBE2I:SUMO2,UBE2I:SUMO3 [nucleoplasm] [CatalystActivity:10605289] SUMO transferase activity of SUMO1:C93-UBE2I [nucleoplasm] [CatalystActivity:10608884] SUMO transferase activity of SUMO2:UBE2I [nucleoplasm]

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