Reactome | Signaling by Erythropoietin

Schema > Pathway > Entries

created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10650406
displayName	Signaling by Erythropoietin
eventOf	[TopLevelPathway:R-DRE-162582] Signal Transduction - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:2266307] erythropoietin-mediated signaling pathway
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-DRE-9709454] EPOR binds EPOR agonists - Danio rerio [Pathway:R-DRE-9027276] Erythropoietin activates Phosphoinositide-3-kinase (PI3K) - Danio rerio
inferredFrom	[Pathway:R-HSA-9006335] Signaling by Erythropoietin - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	Signaling by Erythropoietin
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68323] Danio rerio
stId	R-DRE-9006335
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[TopLevelPathway:R-DRE-162582] Signal Transduction
(inferredTo)	[Pathway:R-HSA-9006335] Signaling by Erythropoietin

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