Reactome | EPOR binds EPOR agonists

Schema > Reaction > Entries

category	binding
compartment	[Compartment:876] plasma membrane [Compartment:984] extracellular region
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10640916
displayName	EPOR binds EPOR agonists
eventOf	[Pathway:R-DRE-9006335] Signaling by Erythropoietin - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9709454] EPOR binds EPOR agonists - Homo sapiens
input	[DefinedSet:R-ALL-9709467] EPOR agonists [extracellular region] [Complex:R-DRE-9006298] EPOR:JAK2:LYN:IRS2 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	EPOR binds EPOR agonists
output	[Complex:R-DRE-9709463] EPOR agonists:EPOR:JAK2:LYN:IRS2 [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-9709454
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DRE-9006335] Signaling by Erythropoietin
(inferredTo)	[Reaction:R-HSA-9709454] EPOR binds EPOR agonists

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