Reactome | Cargo recognition for clathrin-mediated endocytosis

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Cargo recognition for clathrin-mediated endocytosis Show undefined attributes

created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10650290
displayName	Cargo recognition for clathrin-mediated endocytosis
eventOf	[Pathway:R-DRE-8856828] Clathrin-mediated endocytosis - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-DRE-8866277] AP-2 directly binds some endocytic cargo - Danio rerio [Reaction:R-DRE-9681616] AP2 binds chlorpromazine - Danio rerio [Reaction:R-DRE-8863472] DAB2 binds LRP2 - Danio rerio [Reaction:R-DRE-8866268] ADBRK1,2 phosphorylate AVPR2 - Danio rerio [Reaction:R-DRE-8866269] ARRB bind GPCRs - Danio rerio [Reaction:R-DRE-8863718] AGFG1 binds VAMP7 - Danio rerio [Reaction:R-DRE-8863463] STON2 binds SYT proteins - Danio rerio [BlackBoxEvent:R-DRE-8863727] STON2 is neddylated - Danio rerio [Reaction:R-DRE-8863721] NEDD8-STON binds TOR1 hexamer and COP9 complex - Danio rerio [BlackBoxEvent:R-DRE-8863723] COP9 and TOR1 deneddylate STON2 - Danio rerio
inferredFrom	[Pathway:R-HSA-8856825] Cargo recognition for clathrin-mediated endocytosis - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Cargo recognition for clathrin-mediated endocytosis
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68323] Danio rerio
stId	R-DRE-8856825
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(inferredTo)	[Pathway:R-HSA-8856825] Cargo recognition for clathrin-mediated endocytosis
(hasEvent)	[Pathway:R-DRE-8856828] Clathrin-mediated endocytosis

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