Reactome | PTK6 phosphorylates KHDRBS1

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PTK6 phosphorylates KHDRBS1 Show undefined attributes

catalystActivity	[CatalystActivity:10629497] protein tyrosine kinase activity of p-Y342-PTK6:KHDRBS1 [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10629499
displayName	PTK6 phosphorylates KHDRBS1
eventOf	[Pathway:R-DRE-8849468] PTK6 Regulates Proteins Involved in RNA Processing - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DRE-8848993] Phosphorylated KHDRBS1 translocates to the cytosol - Danio rerio
inferredFrom	[Reaction:R-HSA-8848975] PTK6 phosphorylates KHDRBS1 - Homo sapiens
input	3 × [SimpleEntity:R-ALL-29358] ATP [nucleoplasm] [Complex:R-DRE-8848940] p-Y342-PTK6:KHDRBS1 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	PTK6 phosphorylates KHDRBS1
output	3 × [SimpleEntity:R-ALL-113582] ADP [nucleoplasm] [EntityWithAccessionedSequence:R-DRE-8848970] phospho-khdrbs1b [nucleoplasm] [EntityWithAccessionedSequence:R-DRE-8848937] phospho-p-Y342-PTK6 [nucleoplasm]
precedingEvent	[Reaction:R-DRE-8848939] PTK6 binds KHDRBS1 - Danio rerio
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-8848975
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-8849468] PTK6 Regulates Proteins Involved in RNA Processing
(precedingEvent)	[Reaction:R-DRE-8848993] Phosphorylated KHDRBS1 translocates to the cytosol
(inferredTo)	[Reaction:R-HSA-8848975] PTK6 phosphorylates KHDRBS1