Reactome | txna [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-DRE-1250277] Thioredoxin:TXNIP [cytosol] - Danio rerio [Complex:R-DRE-3225859] MAP3K5:TXN [cytosol] - Danio rerio
consumedByEvent	[Reaction:R-DRE-1250264] TXNIP binds reduced thioredoxin - Danio rerio [Reaction:R-DRE-5676940] MSRA reduces L-methyl-(S)-S-oxide to L-Methionine - Danio rerio [Reaction:R-DRE-5676917] MRSBs reduce L-methyl-(R)-S-oxide to L-methionine - Danio rerio [Reaction:R-DRE-111751] RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) - Danio rerio [Reaction:R-DRE-111804] RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) - Danio rerio [Reaction:R-DRE-3697882] PRDX5 reduces peroxynitrite to nitrite using TXN - Danio rerio [Reaction:R-DRE-3341343] PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O - Danio rerio [BlackBoxEvent:R-DRE-1250280] ROS oxidize thioredoxin - Danio rerio
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10563261
displayName	txna [cytosol]
endCoordinate	105
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-66000] TXN [cytosol] - Homo sapiens
maxDepth	1
name	txna TXN Q7ZUI4
referenceEntity	[ReferenceGeneProduct:uniprot:Q7ZUI4] UniProt:Q7ZUI4
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:68323] Danio rerio
stId	R-DRE-66000
startCoordinate	2

(input)	[Reaction:R-DRE-5676940] MSRA reduces L-methyl-(S)-S-oxide to L-Methionine [Reaction:R-DRE-5676917] MRSBs reduce L-methyl-(R)-S-oxide to L-methionine [Reaction:R-DRE-111751] RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) [Reaction:R-DRE-111804] RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) [Reaction:R-DRE-3697882] PRDX5 reduces peroxynitrite to nitrite using TXN [Reaction:R-DRE-3341343] PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O [Reaction:R-DRE-1250264] TXNIP binds reduced thioredoxin [BlackBoxEvent:R-DRE-1250280] ROS oxidize thioredoxin
(hasComponent)	[Complex:R-DRE-1250277] Thioredoxin:TXNIP [cytosol] [Complex:R-DRE-3225859] MAP3K5:TXN [cytosol]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-66000] TXN [cytosol]

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