Reactome | ROS oxidize thioredoxin

Schema > BlackBoxEvent > Entries

category	omitted
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10594423
displayName	ROS oxidize thioredoxin
eventOf	[Pathway:R-DRE-844456] The NLRP3 inflammasome - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-1250280] ROS oxidize thioredoxin - Homo sapiens
input	[SimpleEntity:R-ALL-1250243] ROS [cytosol] [EntityWithAccessionedSequence:R-DRE-66000] txna [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	ROS oxidize thioredoxin
output	[EntityWithAccessionedSequence:R-DRE-73668] txna [cytosol]
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:68323] Danio rerio
stId	R-DRE-1250280
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DRE-844456] The NLRP3 inflammasome
(inferredTo)	[BlackBoxEvent:R-HSA-1250280] ROS oxidize thioredoxin

Cite Us!