Reactome | ABC7, mABC1 and mABC2 mediate heme transport

Schema > Reaction > Entries

ABC7, mABC1 and mABC2 mediate heme transport Show undefined attributes

catalystActivity	[CatalystActivity:10582238] ABC-type heme transporter activity of Heme transporters [mitochondrial inner membrane]
category	transition
compartment	[Compartment:70616] mitochondrial inner membrane [Compartment:70101] cytosol [Compartment:5460] mitochondrial matrix
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10582240
displayName	ABC7, mABC1 and mABC2 mediate heme transport
eventOf	[Pathway:R-DRE-1369007] Mitochondrial ABC transporters - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-382560] ABC7, mABC1 and mABC2 mediate heme transport - Homo sapiens
input	[SimpleEntity:R-ALL-113593] ATP [mitochondrial matrix] [SimpleEntity:R-ALL-113521] H2O [mitochondrial matrix] [SimpleEntity:R-ALL-189444] heme [mitochondrial matrix]
isInDisease	false
isInferred	true
maxDepth	1
name	ABC7, mABC1 and mABC2 mediate heme transport
output	[SimpleEntity:R-ALL-113581] ADP [mitochondrial matrix] [SimpleEntity:R-ALL-71185] ferroheme [cytosol] [SimpleEntity:R-ALL-113548] Pi [mitochondrial matrix]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-382560
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-1369007] Mitochondrial ABC transporters
(inferredTo)	[Reaction:R-HSA-382560] ABC7, mABC1 and mABC2 mediate heme transport

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