Reactome | ERBB2 [plasma membrane]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-DRE-419629] Plexin-B1:ErbB2 [plasma membrane] - Danio rerio [Complex:R-DRE-419627] ERBB2:p-Y-PLXNB1 [plasma membrane] - Danio rerio
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10579371
displayName	ERBB2 [plasma membrane]
endCoordinate	1255
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-372889] ERBB2 [plasma membrane] - Homo sapiens
maxDepth	1
name	ERBB2 Q5EBY4
referenceEntity	[ReferenceGeneProduct:uniprot:Q5EBY4] UniProt:Q5EBY4
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:68323] Danio rerio
stId	R-DRE-372889
startCoordinate	23

(activeUnit)	[CatalystActivity:10579385] protein tyrosine kinase activity of Plexin-B1:ErbB2 [plasma membrane]
(hasComponent)	[Complex:R-DRE-419627] ERBB2:p-Y-PLXNB1 [plasma membrane] [Complex:R-DRE-419629] Plexin-B1:ErbB2 [plasma membrane] [Complex:R-DRE-1918081] Ub-ERBB2:ERBIN:HSP90:CDC37 [plasma membrane] [Complex:R-DRE-1918083] Ub-ERBB2:ERBIN:Ub-HSP90:CDC37 [plasma membrane] [Complex:R-DRE-9652356] ERBB2:TKIs [plasma membrane] [Complex:R-DRE-9665221] ERBB2:trastuzumab [plasma membrane] [Complex:R-DRE-1227970] ERBB2:ERBIN:HSP90:CDC37 [plasma membrane] [Complex:R-DRE-1247502] NRG1/2:ERBB3:ERBB2 [plasma membrane] [Complex:R-DRE-1250312] ERBB2:ERBB4cyt2 heterodimer [plasma membrane] [Complex:R-DRE-1250328] ERBB2:ERBB4cyt1 heterodimers [plasma membrane]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-372889] ERBB2 [plasma membrane]

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