Reactome | ADPRM hydrolyses ADP-ribose to R5P and AMP

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ADPRM hydrolyses ADP-ribose to R5P and AMP Show undefined attributes

catalystActivity	[CatalystActivity:10620002] ADP-ribose diphosphatase activity of ADPRM:Mn2+ [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10620004
displayName	ADPRM hydrolyses ADP-ribose to R5P and AMP
eventOf	[Pathway:R-DRE-2393930] Phosphate bond hydrolysis by NUDT proteins - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5696049] ADPRM hydrolyses ADP-ribose to R5P and AMP - Homo sapiens
input	[SimpleEntity:R-ALL-1131972] ADP-D-ribose [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	ADPRM hydrolyses ADP-ribose to R5P and AMP ADP-D-ribose + H2O => D-ribose 5-phosphate + AMP + 2 H(+)
output	[SimpleEntity:R-ALL-76577] AMP [cytosol] 2 × [SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-73578] R5P [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-5696049
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-2393930] Phosphate bond hydrolysis by NUDT proteins
(inferredTo)	[Reaction:R-HSA-5696049] ADPRM hydrolyses ADP-ribose to R5P and AMP

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