Reactome | Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases

Schema > BlackBoxEvent > Entries

Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases Show undefined attributes

catalystActivity	[CatalystActivity:10859934] aminopeptidase activity of IFN gamma stimulated aminopeptidases [cytosol]
category	omitted
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10859936
displayName	Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases
eventOf	[Pathway:R-DME-983168] Antigen processing: Ubiquitination & Proteasome degradation - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-983162] Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases - Homo sapiens
input	[SimpleEntity:R-ALL-983036] precursor peptide fragment (>16 aa) [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases
output	[SimpleEntity:R-ALL-8942986] L-amino acid [cytosol] [SimpleEntity:R-ALL-983032] oligopeptide fragment (8-16aa) [cytosol]
precedingEvent	[BlackBoxEvent:R-DME-983150] Proteasomal cleavage of substrate - Drosophila melanogaster [BlackBoxEvent:R-DME-9912636] Proteasomal cleavage of intracellular substrate (PA28-alpha-beta-20S proteasome catalyst) - Drosophila melanogaster [BlackBoxEvent:R-DME-9912655] Proteasomal cleavage of intracellular substrate (immunoproteasome catalyst) - Drosophila melanogaster [BlackBoxEvent:R-DME-9912747] Proteasomal clevage of exogenous antigen (immunoproteasome catalyst) - Drosophila melanogaster
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:56210] Drosophila melanogaster
stId	R-DME-983162
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-983168] Antigen processing: Ubiquitination & Proteasome degradation
(inferredTo)	[BlackBoxEvent:R-HSA-983162] Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases

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