Reactome | monophosphorylated RB1 [nucleoplasm]

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monophosphorylated RB1 [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-DME-188373] CCNE:p-T160-CDK2:hypophosphorylated RB1 [nucleoplasm] - Drosophila melanogaster
consumedByEvent	[Reaction:R-DME-188386] Association of Rb with Cyclin E:Cdk2 complexes - Drosophila melanogaster
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10830324
displayName	monophosphorylated RB1 [nucleoplasm]
hasMember	[DefinedSet:R-DME-9687336-3] Homologues of p-S230-RB1 [nucleoplasm] - Drosophila melanogaster [DefinedSet:R-DME-9687343-3] Homologues of p-S249-RB1 [nucleoplasm] - Drosophila melanogaster [DefinedSet:R-DME-9687335-3] Homologues of p-T252-RB1 [nucleoplasm] - Drosophila melanogaster [DefinedSet:R-DME-9687351-3] Homologues of p-S608-RB1 [nucleoplasm] - Drosophila melanogaster [DefinedSet:R-DME-9687352-3] Homologues of p-S612-RB1 [nucleoplasm] - Drosophila melanogaster [DefinedSet:R-DME-9687353-3] Homologues of p-S780-RB1 [nucleoplasm] - Drosophila melanogaster [DefinedSet:R-DME-9687347-3] Homologues of p-S788-RB1 [nucleoplasm] - Drosophila melanogaster [DefinedSet:R-DME-69226-3] Homologues of p-S795-RB1 [nucleoplasm] - Drosophila melanogaster [DefinedSet:R-DME-9687356-3] Homologues of p-S807-RB1 [nucleoplasm] - Drosophila melanogaster [DefinedSet:R-DME-9687354-3] Homologues of p-S811-RB1 [nucleoplasm] - Drosophila melanogaster [DefinedSet:R-DME-9687339-3] Homologues of p-T356-RB1 [nucleoplasm] - Drosophila melanogaster [DefinedSet:R-DME-9687355-3] Homologues of p-T373-RB1 [nucleoplasm] - Drosophila melanogaster [DefinedSet:R-DME-9687357-3] Homologues of p-T821-RB1 [nucleoplasm] - Drosophila melanogaster [DefinedSet:R-DME-9687334-3] Homologues of p-T826-RB1 [nucleoplasm] - Drosophila melanogaster
inDisease	false
inferredFrom	[DefinedSet:R-HSA-9687348] monophosphorylated RB1 [nucleoplasm] - Homo sapiens
maxDepth	3
name	monophosphorylated RB1
producedByEvent	[Reaction:R-DME-69227] Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes - Drosophila melanogaster
schemaClass	DefinedSet
species	[Species:56210] Drosophila melanogaster
stId	R-DME-9687348

Referrals

(input)	[Reaction:R-DME-188386] Association of Rb with Cyclin E:Cdk2 complexes
(hasComponent)	[Complex:R-DME-188373] CCNE:p-T160-CDK2:hypophosphorylated RB1 [nucleoplasm]
(output)	[Reaction:R-DME-69227] Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes
(inferredTo)	[DefinedSet:R-HSA-9687348] monophosphorylated RB1 [nucleoplasm]

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