Reactome | ER Quality Control Compartment (ERQC)

Schema > Pathway > Entries

created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10912260
displayName	ER Quality Control Compartment (ERQC)
eventOf	[Pathway:R-DME-901042] Calnexin/calreticulin cycle - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:6792151] endoplasmic reticulum mannose trimming
hasDiagram	false
hasEHLD	false
hasEvent	[BlackBoxEvent:R-DME-1022127] Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol - Drosophila melanogaster
inferredFrom	[Pathway:R-HSA-901032] ER Quality Control Compartment (ERQC) - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	ER Quality Control Compartment (ERQC)
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:56210] Drosophila melanogaster
stId	R-DME-901032
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DME-901042] Calnexin/calreticulin cycle
(inferredTo)	[Pathway:R-HSA-901032] ER Quality Control Compartment (ERQC)

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