Reactome | FOXA1 and GATA3 bind to CCND1 promoter

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FOXA1 and GATA3 bind to CCND1 promoter Show undefined attributes

category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10901282
displayName	FOXA1 and GATA3 bind to CCND1 promoter
eventOf	[Pathway:R-DME-9018519] Estrogen-dependent gene expression - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9009065] FOXA1 and GATA3 bind to CCND1 promoter - Homo sapiens
input	[Complex:R-DME-9009060] CCND1 gene:H3K4me2 nucleosome:YY1:HDAC1 [nucleoplasm] [EntityWithAccessionedSequence:R-DME-453074] fkh [nucleoplasm] [DefinedSet:R-DME-996768-5] Homologues of GATA3 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	FOXA1 and GATA3 bind to CCND1 promoter
output	[Complex:R-DME-9009057] CCND1 gene:H3K4me2 nucleosome:FOXA1:GATA3 [nucleoplasm] [EntityWithAccessionedSequence:R-DME-205021] HDAC1 [nucleoplasm] [EntityWithAccessionedSequence:R-DME-4086091] pho [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-9009065
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-9018519] Estrogen-dependent gene expression
(inferredTo)	[Reaction:R-HSA-9009065] FOXA1 and GATA3 bind to CCND1 promoter

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