Reactome | Mtr4 [nucleoplasm]

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-DME-9930036] PAXT connection [nucleoplasm] - Drosophila melanogaster [Complex:R-DME-8985567] RBM7:ZCCHC8:SKIV2L2 [nucleoplasm] - Drosophila melanogaster [Complex:R-DME-6791581] EXOSC10:C1D:MPHOSPH6:SKIV2L2:Exosome [nucleoplasm] - Drosophila melanogaster [Complex:R-DME-9769528] Spliceosomal Pre-B complex [nucleoplasm] - Drosophila melanogaster [Complex:R-DME-9770126] Spliceosomal B complex [nucleoplasm] - Drosophila melanogaster [Complex:R-DME-9769560] Spliceosomal Bact complex [nucleoplasm] - Drosophila melanogaster [Complex:R-DME-9794539] Spliceosomal B* complex [nucleoplasm] - Drosophila melanogaster [Complex:R-DME-9770138] Spliceosomal C complex [nucleoplasm] - Drosophila melanogaster [Complex:R-DME-9770118] Spliceosomal C* complex [nucleoplasm] - Drosophila melanogaster
consumedByEvent	[Reaction:R-DME-9933559] The PAXT connection (ZFC3H1:MTREX, ZFC3H1:MTR4), RBM26, RBM27, PAPOLG, YTHDC1, and YTHDC2 bind CBCA:polyadenylated m7GpppN-RNA:PABPN1 - Drosophila melanogaster
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10886527
displayName	Mtr4 [nucleoplasm]
endCoordinate	1042
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-6791189] SKIV2L2 [nucleoplasm] - Homo sapiens
isRequired	[Requirement:10886917] Requirement by 'SKIV2L2 [nucleoplasm]'
maxDepth	1
name	Mtr4 SKIV2L2 Q9Y134
positivelyRegulates	[Requirement:10886917] Requirement by 'SKIV2L2 [nucleoplasm]'
producedByEvent	[BlackBoxEvent:R-DME-9770236] Formation of the Spliceosomal P complex and exon ligation - Drosophila melanogaster
referenceEntity	[ReferenceGeneProduct:uniprot:Q9Y134] UniProt:Q9Y134
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:56210] Drosophila melanogaster
stId	R-DME-6791189
startCoordinate	2

(regulator)	[Requirement:10886917] Requirement by 'SKIV2L2 [nucleoplasm]'
(hasComponent)	[Complex:R-DME-6791581] EXOSC10:C1D:MPHOSPH6:SKIV2L2:Exosome [nucleoplasm] [Complex:R-DME-9930036] PAXT connection [nucleoplasm] [Complex:R-DME-8985567] RBM7:ZCCHC8:SKIV2L2 [nucleoplasm] [Complex:R-DME-9769528] Spliceosomal Pre-B complex [nucleoplasm] [Complex:R-DME-9770126] Spliceosomal B complex [nucleoplasm] [Complex:R-DME-9769560] Spliceosomal Bact complex [nucleoplasm] [Complex:R-DME-9794539] Spliceosomal B* complex [nucleoplasm] [Complex:R-DME-9770138] Spliceosomal C complex [nucleoplasm] [Complex:R-DME-9770118] Spliceosomal C* complex [nucleoplasm]
(input)	[Reaction:R-DME-9933559] The PAXT connection (ZFC3H1:MTREX, ZFC3H1:MTR4), RBM26, RBM27, PAPOLG, YTHDC1, and YTHDC2 bind CBCA:polyadenylated m7GpppN-RNA:PABPN1
(output)	[BlackBoxEvent:R-DME-9770236] Formation of the Spliceosomal P complex and exon ligation
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-6791189] SKIV2L2 [nucleoplasm]

Mtr4 [nucleoplasm] Show undefined attributes

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