Reactome | Formation of the Spliceosomal P complex and exon ligation

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Formation of the Spliceosomal P complex and exon ligation Show undefined attributes

catalystActivity	[CatalystActivity:10906097] second spliceosomal transesterification activity of Spliceosomal C* complex [nucleoplasm]
category	omitted
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10906099
displayName	Formation of the Spliceosomal P complex and exon ligation
eventOf	[Pathway:R-DME-72163] mRNA Splicing - Major Pathway - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-9770236] Formation of the Spliceosomal P complex and exon ligation - Homo sapiens
input	[EntityWithAccessionedSequence:R-DME-9769590] Dmel\CG12818 [nucleoplasm] [EntityWithAccessionedSequence:R-DME-9769588] Dmel\CG7974 [nucleoplasm] [EntityWithAccessionedSequence:R-DME-9769602] Nkap [nucleoplasm] [Complex:R-DME-9770118] Spliceosomal C* complex [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	Formation of the Spliceosomal P complex and exon ligation Second catalytic step of mRNA splicing
output	[EntityWithAccessionedSequence:R-DME-9769562] CYC4 [nucleoplasm] [EntityWithAccessionedSequence:R-DME-8849139] DDX39B [nucleoplasm] [EntityWithAccessionedSequence:R-DME-6791189] Mtr4 [nucleoplasm] [EntityWithAccessionedSequence:R-DME-8952113] Ppil4 [nucleoplasm] [EntityWithAccessionedSequence:R-DME-5688093] Prp18 [nucleoplasm] [Complex:R-DME-9769587] Spliceosomal P complex [nucleoplasm]
precedingEvent	[BlackBoxEvent:R-DME-9770141] Formation of the Spliceosomal C* complex - Drosophila melanogaster
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:56210] Drosophila melanogaster
stId	R-DME-9770236
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-72163] mRNA Splicing - Major Pathway
(inferredTo)	[BlackBoxEvent:R-HSA-9770236] Formation of the Spliceosomal P complex and exon ligation

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