Reactome | phospho-Pli [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-DME-975166] p-Pellino:hp-IRAK1:TRAF6 [endosome membrane] - Drosophila melanogaster [Complex:R-DME-451410] IRAK4: p-Pellino-1,2,3 [cytosol] - Drosophila melanogaster
consumedByEvent	[Reaction:R-DME-975142] Pellino binds hp-IRAK1:TRAF6 upon TLR7/8 or 9 activation - Drosophila melanogaster [Reaction:R-DME-937044] Pellino binds hp-IRAK1:TRAF6 - Drosophila melanogaster
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10854758
displayName	phospho-Pli [cytosol]
endCoordinate	418
hasModifiedResidue	[ModifiedResidue:10854756] phosphorylated residue at unknown position
inDisease	false
inferredFrom	[CandidateSet:R-HSA-450819] p-Pellino-1,2,(3) [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-450815] p-PELI1 [cytosol] - Homo sapiens
maxDepth	1
name	phospho-Pli p-PELI1 O77237
producedByEvent	[Reaction:R-DME-975122] Pellino ubiquitinates hp-IRAK1 upon TLR7/8 or 9 activation - Drosophila melanogaster [BlackBoxEvent:R-DME-8948066] K63polyUb-IRAK1 dissociates - Drosophila melanogaster [Reaction:R-DME-937050] Pellino ubiquitinates hp-IRAK1 - Drosophila melanogaster
referenceEntity	[ReferenceGeneProduct:uniprot:O77237] UniProt:O77237
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:56210] Drosophila melanogaster
stId	R-DME-450815
startCoordinate	1

(output)	[Reaction:R-DME-975122] Pellino ubiquitinates hp-IRAK1 upon TLR7/8 or 9 activation [BlackBoxEvent:R-DME-8948066] K63polyUb-IRAK1 dissociates [Reaction:R-DME-937050] Pellino ubiquitinates hp-IRAK1
(activeUnit)	[CatalystActivity:10858705] ubiquitin-ubiquitin ligase activity of p-Pellino:hp-IRAK1:TRAF6 [endosome membrane] [CatalystActivity:10858469] ubiquitin-ubiquitin ligase activity of p-Pellino:hp-IRAK1:TRAF6 [plasma membrane]
(input)	[Reaction:R-DME-975142] Pellino binds hp-IRAK1:TRAF6 upon TLR7/8 or 9 activation [Reaction:R-DME-937044] Pellino binds hp-IRAK1:TRAF6
(hasComponent)	[Complex:R-DME-975166] p-Pellino:hp-IRAK1:TRAF6 [endosome membrane] [Complex:R-DME-451410] IRAK4: p-Pellino-1,2,3 [cytosol] [Complex:R-DME-8948061] K63polyUb-hp-IRAK1:p-Pellino-1,2,(3) [cytosol] [Complex:R-DME-451411] hp-IRAK1: p-Pellino-1,2,(3) [cytosol] [Complex:R-DME-937020] TRAF6:hp-IRAK1:Pellino [plasma membrane]
(inferredTo)	[CandidateSet:R-HSA-450819] p-Pellino-1,2,(3) [cytosol] [EntityWithAccessionedSequence:R-HSA-450815] p-PELI1 [cytosol]