Reactome | Synthesis of GDP-mannose

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Synthesis of GDP-mannose Show undefined attributes

created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10912096
displayName	Synthesis of GDP-mannose
eventOf	[Pathway:R-DME-446219] Synthesis of substrates in N-glycan biosythesis - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:25497] GDP-mannose biosynthetic process
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-DME-532549] MPI isomerises Fru6P to Man6P - Drosophila melanogaster [Reaction:R-DME-9909159] HK1 phosphorylates Mannose to Man6P - Drosophila melanogaster [Reaction:R-DME-446201] PMM1,2 isomerise Man6P to Man1P - Drosophila melanogaster [Reaction:R-DME-446221] GMPPB converts Mannose-1-phosphate to GDP-Mannose - Drosophila melanogaster
inferredFrom	[Pathway:R-HSA-446205] Synthesis of GDP-mannose - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Synthesis of GDP-mannose
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:56210] Drosophila melanogaster
stId	R-DME-446205
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-446219] Synthesis of substrates in N-glycan biosythesis
(inferredTo)	[Pathway:R-HSA-446205] Synthesis of GDP-mannose

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