Reactome | PMM1,2 isomerise Man6P to Man1P

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PMM1,2 isomerise Man6P to Man1P Show undefined attributes

catalystActivity	[CatalystActivity:10854013] phosphomannomutase activity of PMM1,2 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10854015
displayName	PMM1,2 isomerise Man6P to Man1P
eventOf	[Pathway:R-DME-446205] Synthesis of GDP-mannose - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DME-446221] GMPPB converts Mannose-1-phosphate to GDP-Mannose - Drosophila melanogaster
inferredFrom	[Reaction:R-HSA-446201] PMM1,2 isomerise Man6P to Man1P - Homo sapiens
input	[SimpleEntity:R-ALL-532562] Man6P [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	PMM1,2 isomerise Man6P to Man1P D-mannose 6-phosphate => alpha-D-mannose 1-phosphate Mannose 6-phosphate isomerises to Mannose 1-phosphate
output	[SimpleEntity:R-ALL-532531] Man1P [cytosol]
precedingEvent	[Reaction:R-DME-9909159] HK1 phosphorylates Mannose to Man6P - Drosophila melanogaster [Reaction:R-DME-532549] MPI isomerises Fru6P to Man6P - Drosophila melanogaster
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-446201
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-446205] Synthesis of GDP-mannose
(precedingEvent)	[Reaction:R-DME-446221] GMPPB converts Mannose-1-phosphate to GDP-Mannose
(inferredTo)	[Reaction:R-HSA-446201] PMM1,2 isomerise Man6P to Man1P

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