Reactome | Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs)

Schema > Reaction > Entries

Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) Show undefined attributes

catalystActivity	[CatalystActivity:10853360] protein serine/threonine kinase activity of p-S221,T359,S363,S380,T573,T732-RSK [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10853362
displayName	Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs)
eventOf	[Pathway:R-DME-442742] CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-442724] Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) - Homo sapiens
input	[SimpleEntity:R-ALL-29358] ATP [nucleoplasm] [EntityWithAccessionedSequence:R-DME-52777] CrebB [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs)
output	[SimpleEntity:R-ALL-113582] ADP [nucleoplasm] [EntityWithAccessionedSequence:R-DME-111910] phospho-CrebB [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-442724
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-442742] CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling
(inferredTo)	[Reaction:R-HSA-442724] Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs)

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