Reactome | CDC42:GTP, RAC1:GTP [plasma membrane]

Schema > DefinedSet > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-DME-389782] PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] - Drosophila melanogaster
consumedByEvent	[Reaction:R-DME-389788] Activation of PAKs by RAC1 and CDC42 - Drosophila melanogaster [Reaction:R-DME-8981931] RAC1 and CDC42 activate PAK2 - Drosophila melanogaster [Reaction:R-DME-8981926] RAC1 and CDC42 activate PAK3 - Drosophila melanogaster [Reaction:R-DME-2029456] RAC1 and CDC42 activate PAK1 - Drosophila melanogaster
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10849363
displayName	CDC42:GTP, RAC1:GTP [plasma membrane]
hasMember	[Complex:R-DME-182921] CDC42:GTP [plasma membrane] - Drosophila melanogaster [Complex:R-DME-351067] RAC1:GTP [plasma membrane] - Drosophila melanogaster
inDisease	false
inferredFrom	[DefinedSet:R-HSA-389778] CDC42:GTP, RAC1:GTP [plasma membrane] - Homo sapiens
maxDepth	3
name	CDC42:GTP, RAC1:GTP Active RAC1/CDC42
producedByEvent	[Reaction:R-DME-2029454] Autophosphorylation of PAK1 - Drosophila melanogaster [Reaction:R-DME-5627775] Autophosphorylation of PAK1,2,3 - Drosophila melanogaster [Reaction:R-DME-5627775] Autophosphorylation of PAK1,2,3 - Drosophila melanogaster [Reaction:R-DME-5627775] Autophosphorylation of PAK1,2,3 - Drosophila melanogaster
schemaClass	DefinedSet
species	[Species:56210] Drosophila melanogaster
stId	R-DME-389778

(hasComponent)	[Complex:R-DME-389782] PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] [Complex:R-DME-8981927] CDC42:GTP,RAC1:GTP:PAK2 [plasma membrane] [Complex:R-DME-8981928] CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane] [Complex:R-DME-2029159] RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane]
(input)	[Reaction:R-DME-389788] Activation of PAKs by RAC1 and CDC42 [Reaction:R-DME-8981931] RAC1 and CDC42 activate PAK2 [Reaction:R-DME-8981926] RAC1 and CDC42 activate PAK3 [Reaction:R-DME-2029456] RAC1 and CDC42 activate PAK1
(output)	[Reaction:R-DME-2029454] Autophosphorylation of PAK1 [Reaction:R-DME-5627775] Autophosphorylation of PAK1,2,3
(inferredTo)	[DefinedSet:R-HSA-389778] CDC42:GTP, RAC1:GTP [plasma membrane]