Reactome | RAC1:GTP [plasma membrane]

Schema > Complex > Entries

RAC1:GTP [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-DME-9013182] RAC1:GTP:RAC1 effectors [plasma membrane] - Drosophila melanogaster [Complex:R-DME-5218784] p-VAV family:PIP3:RAC1:GTP [plasma membrane] - Drosophila melanogaster [Complex:R-DME-2029148] p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] - Drosophila melanogaster [Complex:R-DME-2029147] WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] - Drosophila melanogaster [Complex:R-DME-450786] PK:VANG:STAN dimer:FZ:DSH:DGO:RAC1:GTP [plasma membrane] - Drosophila melanogaster
consumedByEvent	[BlackBoxEvent:R-DME-9691168] RAC1 translocates to the endoplasmic reticulum membrane - Drosophila melanogaster [Reaction:R-DME-9013144] RAC1 GAPs stimulate RAC1 GTPase activity - Drosophila melanogaster [Reaction:R-DME-9013145] RAC1 binds effectors at the plasma membrane - Drosophila melanogaster [Reaction:R-DME-445072] Interaction of PAK1 with Rac1-GTP - Drosophila melanogaster [Reaction:R-DME-350385] DSH binds to RAC1:GTP - Drosophila melanogaster [Reaction:R-DME-2029465] RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) - Drosophila melanogaster
created	[InstanceEdit:351030] Williams, MG, 2008-05-21 13:47:52
dbId	351067
displayName	RAC1:GTP [plasma membrane]
hasComponent	[SimpleEntity:R-ALL-29438] GTP [cytosol] [EntityWithAccessionedSequence:R-DME-351103] RAC1 [plasma membrane]
inDisease	false
includedLocation	[Compartment:70101] cytosol
inferredFrom	[DefinedSet:R-HSA-9615275] RAC1:GTP,RAC2:GTP,RHOG:GTP [plasma membrane] - Homo sapiens [Complex:R-HSA-442641] RAC1:GTP [plasma membrane] - Homo sapiens
maxDepth	2
memberOf	[CandidateSet:R-DME-9959034] RAC1:GTP,(CDC42:GTP) [plasma membrane] - Drosophila melanogaster [DefinedSet:R-DME-8981458] RHOA,RHOB,RHOC,RAC1:GTP [plasma membrane] - Drosophila melanogaster
modified	[InstanceEdit:8879177] Wu, G, 2016-07-15
name	RAC1:GTP
producedByEvent	[Reaction:R-DME-9013143] RAC1 GEFs activate RAC1 - Drosophila melanogaster [Reaction:R-DME-1433415] Activation of RAC1 - Drosophila melanogaster [Reaction:R-DME-4093336] p-TIAM1 exchanges GTP for GDP on RAC1, activating it - Drosophila melanogaster [Reaction:R-DME-3928628] VAV exchanges GTP for GDP on RAC1, activating it - Drosophila melanogaster [Reaction:R-DME-3928642] TIAM1 exchanges GTP for GDP on RAC1, activating it - Drosophila melanogaster [Reaction:R-DME-445064] Activation of Rac1 by VAV2 - Drosophila melanogaster [Reaction:R-DME-2424476] Activation of RAC1 by VAV2/3 - Drosophila melanogaster [Reaction:R-DME-8848618] Activation of RAC1 by the PXN:CRK complex - Drosophila melanogaster
schemaClass	Complex
species	[Species:56210] Drosophila melanogaster
stId	R-DME-351067

Referrals

(input)	[Reaction:R-DME-350385] DSH binds to RAC1:GTP [BlackBoxEvent:R-DME-9691168] RAC1 translocates to the endoplasmic reticulum membrane [Reaction:R-DME-9013144] RAC1 GAPs stimulate RAC1 GTPase activity [Reaction:R-DME-9013145] RAC1 binds effectors at the plasma membrane [Reaction:R-DME-445072] Interaction of PAK1 with Rac1-GTP [Reaction:R-DME-2029465] RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC)
(hasComponent)	[Complex:R-DME-450786] PK:VANG:STAN dimer:FZ:DSH:DGO:RAC1:GTP [plasma membrane] [Complex:R-DME-9013182] RAC1:GTP:RAC1 effectors [plasma membrane] [Complex:R-DME-445001] pPAK1:Rac1-GTP [cytosol] [Complex:R-DME-5663231] RAC1:GTP:FMNL1 [plasma membrane] [Complex:R-DME-5218784] p-VAV family:PIP3:RAC1:GTP [plasma membrane] [Complex:R-DME-2029147] WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] [Complex:R-DME-2130182] p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] [Complex:R-DME-2029148] p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] [Complex:R-DME-2685706] p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane]
(output)	[Reaction:R-DME-9013143] RAC1 GEFs activate RAC1 [Reaction:R-DME-4093336] p-TIAM1 exchanges GTP for GDP on RAC1, activating it [Reaction:R-DME-3928628] VAV exchanges GTP for GDP on RAC1, activating it [Reaction:R-DME-3928642] TIAM1 exchanges GTP for GDP on RAC1, activating it [Reaction:R-DME-445064] Activation of Rac1 by VAV2 [Reaction:R-DME-1433415] Activation of RAC1 [Reaction:R-DME-2424476] Activation of RAC1 by VAV2/3 [Reaction:R-DME-8848618] Activation of RAC1 by the PXN:CRK complex
(hasMember)	[DefinedSet:R-DME-8981458] RHOA,RHOB,RHOC,RAC1:GTP [plasma membrane] [DefinedSet:R-DME-389778] CDC42:GTP, RAC1:GTP [plasma membrane] [CandidateSet:R-DME-9959034] RAC1:GTP,(CDC42:GTP) [plasma membrane]
(inferredTo)	[DefinedSet:R-HSA-9615275] RAC1:GTP,RAC2:GTP,RHOG:GTP [plasma membrane] [Complex:R-HSA-442641] RAC1:GTP [plasma membrane]

© 2026 Reactome

Cite Us!