Reactome | SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space)

Schema > Reaction > Entries

SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) Show undefined attributes

catalystActivity	[CatalystActivity:10874206] superoxide dismutase activity of SOD1 dimer [mitochondrial intermembrane space]
category	transition
compartment	[Compartment:17927] mitochondrial intermembrane space
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10874208
displayName	SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space)
eventOf	[Pathway:R-DME-3299685] Detoxification of Reactive Oxygen Species - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-3777112] SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) - Homo sapiens
input	2 × [SimpleEntity:R-ALL-163953] H+ [mitochondrial intermembrane space] 2 × [SimpleEntity:R-ALL-3341308] O2- [mitochondrial intermembrane space]
isInDisease	false
isInferred	true
maxDepth	1
name	SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space)
output	[SimpleEntity:R-ALL-189481] H2O2 [mitochondrial intermembrane space] [SimpleEntity:R-ALL-189461] O2 [mitochondrial intermembrane space]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-3777112
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-3299685] Detoxification of Reactive Oxygen Species
(inferredTo)	[Reaction:R-HSA-3777112] SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space)

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