Reactome | COQ7:COQ9 octamer hydroxylates DMQ10H2

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COQ7:COQ9 octamer hydroxylates DMQ10H2 Show undefined attributes

catalystActivity	[CatalystActivity:10870232] oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen of COQ3:COQ4:COQ5:COQ6:COQ7:COQ9 [mitochondrial inner membrane]
category	transition
compartment	[Compartment:70616] mitochondrial inner membrane [Compartment:5460] mitochondrial matrix
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10870236
displayName	COQ7:COQ9 octamer hydroxylates DMQ10H2
eventOf	[Pathway:R-DME-2142789] Ubiquinol biosynthesis - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DME-2162186] COQ3 methylates DeMQ10H2 - Drosophila melanogaster
inferredFrom	[Reaction:R-HSA-2162194] COQ7:COQ9 octamer hydroxylates DMQ10H2 - Homo sapiens
input	[SimpleEntity:R-ALL-2162204] DMQ10H2 [mitochondrial inner membrane] [SimpleEntity:R-ALL-113529] H+ [mitochondrial matrix] [SimpleEntity:R-ALL-29362] NADH [mitochondrial matrix] [SimpleEntity:R-ALL-113533] O2 [mitochondrial matrix]
isInDisease	false
isInferred	true
maxDepth	1
name	COQ7:COQ9 octamer hydroxylates DMQ10H2 DMQ10H2 is hydroxylated to DeMQ10H2 by COQ7
output	[SimpleEntity:R-ALL-2162212] DeMQ10H2 [mitochondrial inner membrane] [SimpleEntity:R-ALL-113521] H2O [mitochondrial matrix] [SimpleEntity:R-ALL-113526] NAD+ [mitochondrial matrix]
precedingEvent	[Reaction:R-DME-2162188] COQ5 methylates MDMQ10H2 - Drosophila melanogaster
regulatedBy	[Requirement:10870237] Requirement by 'COQ8A,B:COQ7:COQ9 [mitochondrial inner membrane]'
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-2162194
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-2142789] Ubiquinol biosynthesis
(precedingEvent)	[Reaction:R-DME-2162186] COQ3 methylates DeMQ10H2
(inferredTo)	[Reaction:R-HSA-2162194] COQ7:COQ9 octamer hydroxylates DMQ10H2