Phosphorylated HOP phosphorylates DOME

Stable Identifier
R-DME-209160
Type
Reaction [transition]
Species
Drosophila melanogaster
Compartment
cytosol, plasma membrane
ReviewStatus
5/5
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Phosphorylated HOP phosphorylates DOME
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Tyr966 on the cytoplasmic tail of the DOME receptor is phosphorylated by phosphorylated HOP.
Literature References
PubMed ID Title Journal Year
9620640 Signaling mechanisms through gp130: a model of the cytokine system

Hirano, T, Nakajima, K, Hibi, M

Cytokine Growth Factor Rev 1997
9047382 An alternative pathway for STAT activation that is mediated by the direct interaction between JAK and STAT

Fujitani, Y, Hibi, M, Fukada, T, Takahashi-Tezuka, M, Yoshida, H, Yamaguchi, T, Sugiyama, K, Yamanaka, Y, Nakajima, K, Hirano, T

Oncogene 1997
11825879 mom identifies a receptor for the Drosophila JAK/STAT signal transduction pathway and encodes a protein distantly related to the mammalian cytokine receptor family

Chen, HW, Chen, X, Oh, SW, Marinissen, MJ, Gutkind, JS, Hou, SX

Genes Dev 2002
Participants
Input
Output
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as an event of
Catalyst Activity

protein tyrosine kinase activity of Phospho HOP:DOME:UPD:DOME:Phospho HOP [plasma membrane]

Physical Entity
Phospho HOP:DOME:UPD:DOME:Phospho HOP [plasma membrane] (Drosophila melanogaster)
Activity
protein tyrosine kinase activity (GO:0004713)
Authored
Williams, MG  (2006-11-02)
Reviewed
Perrimon, N  (2008-01-16)
Created
Williams, MG  (2006-11-03)
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