Reactome | The activation of arylsulfatases

Schema > Pathway > Entries

created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10912406
displayName	The activation of arylsulfatases
eventOf	[Pathway:R-DME-163841] Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-DME-1614362] SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases - Drosophila melanogaster
inferredFrom	[Pathway:R-HSA-1663150] The activation of arylsulfatases - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	The activation of arylsulfatases
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:56210] Drosophila melanogaster
stId	R-DME-1663150
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DME-163841] Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation
(inferredTo)	[Pathway:R-HSA-1663150] The activation of arylsulfatases

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