Reactome | Signal transduction by L1

Schema > Pathway > Entries

created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11049236
displayName	Signal transduction by L1
eventOf	[Pathway:R-DDI-373760] L1CAM interactions - Dictyostelium discoideum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-DDI-445072] Interaction of PAK1 with Rac1-GTP - Dictyostelium discoideum [Reaction:R-DDI-109860] MAP2K1 phosphorylates MAPK3 - Dictyostelium discoideum [Reaction:R-DDI-109862] MAP2K2 phosphorylates MAPK1 - Dictyostelium discoideum
inferredFrom	[Pathway:R-HSA-445144] Signal transduction by L1 - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Signal transduction by L1
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-445144
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DDI-373760] L1CAM interactions
(inferredTo)	[Pathway:R-HSA-445144] Signal transduction by L1

Cite Us!