Reactome | Interaction of PAK1 with Rac1-GTP

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Interaction of PAK1 with Rac1-GTP Show undefined attributes

catalystActivity	[CatalystActivity:11011746] protein serine/threonine kinase activity of PAK1 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11011748
displayName	Interaction of PAK1 with Rac1-GTP
eventOf	[Pathway:R-DDI-445144] Signal transduction by L1 - Dictyostelium discoideum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-445072] Interaction of PAK1 with Rac1-GTP - Homo sapiens
input	2 × [SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-DDI-445002] PAK1 dimer [cytosol] [Complex:R-DDI-442641] RAC1:GTP [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Interaction of PAK1 with Rac1-GTP
output	2 × [SimpleEntity:R-ALL-29370] ADP [cytosol] [DefinedSet:R-DDI-162629-5] Homologues of PAK1 [cytosol] [Complex:R-DDI-445001] pPAK1:Rac1-GTP [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-445072
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DDI-445144] Signal transduction by L1
(inferredTo)	[Reaction:R-HSA-445072] Interaction of PAK1 with Rac1-GTP

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