Reactome | Vasopressin regulates renal water homeostasis via Aquaporins

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Vasopressin regulates renal water homeostasis via Aquaporins Show undefined attributes

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11049294
displayName	Vasopressin regulates renal water homeostasis via Aquaporins
eventOf	[Pathway:R-DDI-445717] Aquaporin-mediated transport - Dictyostelium discoideum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:260622] renal water homeostasis
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-DDI-8951727] cAMP binds PKA tetramer - Dictyostelium discoideum [Reaction:R-DDI-111925] cAMP induces dissociation of inactive PKA tetramers - Dictyostelium discoideum [Reaction:R-DDI-432232] Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) - Dictyostelium discoideum [Reaction:R-DDI-432010] Aquaporin-1 passively transports water into cell - Dictyostelium discoideum [Reaction:R-DDI-432065] p-S256-Aquaporin-2 passively transports water into cell - Dictyostelium discoideum [Reaction:R-DDI-432054] Aquaporin-1 passively transports water out of cell - Dictyostelium discoideum [Reaction:R-DDI-432067] Aquaporin-4 passively transports water out of cell - Dictyostelium discoideum
inferredFrom	[Pathway:R-HSA-432040] Vasopressin regulates renal water homeostasis via Aquaporins - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Vasopressin regulates renal water homeostasis via Aquaporins
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-432040
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DDI-445717] Aquaporin-mediated transport
(inferredTo)	[Pathway:R-HSA-432040] Vasopressin regulates renal water homeostasis via Aquaporins