Reactome | NAGLU hydrolyses heparan chain(2)

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NAGLU hydrolyses heparan chain(2) Show undefined attributes

catalystActivity	[CatalystActivity:11017943] alpha-N-acetylglucosaminidase activity of NAGLU(59-743) [lysosomal lumen]
category	transition
compartment	[Compartment:161320] lysosomal lumen
created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11018876
displayName	NAGLU hydrolyses heparan chain(2)
eventOf	[Pathway:R-DDI-2024096] HS-GAG degradation - Dictyostelium discoideum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-2090038] NAGLU hydrolyses heparan chain(2) - Homo sapiens
input	[SimpleEntity:R-ALL-2090053] GlcNAc- group [lysosomal lumen] [SimpleEntity:R-ALL-1605715] H2O [lysosomal lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	NAGLU hydrolyses heparan chain(2)
output	[SimpleEntity:R-ALL-9941448] -R [lysosomal lumen] [SimpleEntity:R-ALL-1678743] GlcNAc [lysosomal lumen]
precedingEvent	[Reaction:R-DDI-2090085] HGSNAT oligomer acetylates Heparan chain(1) - Dictyostelium discoideum
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-2090038
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DDI-2024096] HS-GAG degradation
(inferredTo)	[Reaction:R-HSA-2090038] NAGLU hydrolyses heparan chain(2)

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