Reactome | Signaling by VEGF

Schema > Pathway > Entries

created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11049632
displayName	Signaling by VEGF
eventOf	[Pathway:R-DDI-9006934] Signaling by Receptor Tyrosine Kinases - Dictyostelium discoideum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:180] vascular endothelial growth factor receptor signaling pathway
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-DDI-4420097] VEGFA-VEGFR2 Pathway - Dictyostelium discoideum
inferredFrom	[Pathway:R-HSA-194138] Signaling by VEGF - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	4
name	Signaling by VEGF Signaling by Vascular Epithelial Growth Factors (VEGF)
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-194138
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DDI-9006934] Signaling by Receptor Tyrosine Kinases
(hasEncapsulatedEvent)	[Pathway:R-DDI-5668599] RHO GTPases Activate NADPH Oxidases [Pathway:R-DDI-9833482] PKR-mediated signaling
(inferredTo)	[Pathway:R-HSA-194138] Signaling by VEGF

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