Reactome | Signaling by VEGF

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Signaling by VEGF Show undefined attributes

authored	[InstanceEdit:4420157] Garapati, P V, 2013-08-30
created	[InstanceEdit:194137] Gopinathrao, G, 2007-03-08 15:44:44
dbId	194138
displayName	Signaling by VEGF
edited	[InstanceEdit:4420157] Garapati, P V, 2013-08-30
eventOf	[Pathway:R-HSA-9006934] Signaling by Receptor Tyrosine Kinases - Homo sapiens
figure	[Figure:195440] /figures/vegfsig1.jpg
goBiologicalProcess	[GO_BiologicalProcess:180] vascular endothelial growth factor receptor signaling pathway
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-HSA-194313] VEGF ligand-receptor interactions - Homo sapiens [Pathway:R-HSA-4420097] VEGFA-VEGFR2 Pathway - Homo sapiens [Pathway:R-HSA-194306] Neuropilin interactions with VEGF and VEGFR - Homo sapiens [BlackBoxEvent:R-HSA-9674532] AAMP gene expression is positively regulated by VEGF - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2023-03-29
literatureReference	[LiteratureReference:195436] Signal transduction by VEGF receptors in regulation of angiogenesis and lymphangiogenesis [LiteratureReference:195439] Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis [LiteratureReference:195474] VEGF-receptor signal transduction [LiteratureReference:195479] Signal transduction via vascular endothelial growth factor (VEGF) receptors and their roles in atherogenesis
maxDepth	4
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	Signaling by VEGF Signaling by Vascular Epithelial Growth Factors (VEGF)
orthologousEvent	[Pathway:R-MMU-194138] Signaling by VEGF - Mus musculus [Pathway:R-RNO-194138] Signaling by VEGF - Rattus norvegicus [Pathway:R-CFA-194138] Signaling by VEGF - Canis familiaris [Pathway:R-SSC-194138] Signaling by VEGF - Sus scrofa [Pathway:R-DRE-194138] Signaling by VEGF - Danio rerio [Pathway:R-XTR-194138] Signaling by VEGF - Xenopus tropicalis [Pathway:R-GGA-194138] Signaling by VEGF - Gallus gallus [Pathway:R-CEL-194138] Signaling by VEGF - Caenorhabditis elegans [Pathway:R-SPO-194138] Signaling by VEGF - Schizosaccharomyces pombe [Pathway:R-SCE-194138] Signaling by VEGF - Saccharomyces cerevisiae [Pathway:R-DME-194138] Signaling by VEGF - Drosophila melanogaster [Pathway:R-DDI-194138] Signaling by VEGF - Dictyostelium discoideum [Pathway:R-PFA-194138] Signaling by VEGF - Plasmodium falciparum [Pathway:R-BTA-194138] Signaling by VEGF - Bos taurus
releaseDate	2008-03-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:215257] Claesson-Welsh, L, 2008-02-28 00:15:17
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-194138
summation	[Summation:195441] In normal development vascular endothelial growth factors (V...
updateTrackers	[UpdateTracker:9782019] Update Tracker - [Pathway:194138] Signaling by VEGF - v60:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9784555] Update Tracker - [Pathway:194138] Signaling by VEGF - v53:[updateContainedPathway] [UpdateTracker:9784982] Update Tracker - [Pathway:194138] Signaling by VEGF - v52:[updateIndirectRLE] [UpdateTracker:9783107] Update Tracker - [Pathway:194138] Signaling by VEGF - v57:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9777129] Update Tracker - [Pathway:194138] Signaling by VEGF - v72:[addHasEvent] [UpdateTracker:9786599] Update Tracker - [Pathway:194138] Signaling by VEGF - v49:[addHasEvent, updateContainedPathway] [UpdateTracker:9778718] Update Tracker - [Pathway:194138] Signaling by VEGF - v67:[updateIndirectRLE] [UpdateTracker:9786225] Update Tracker - [Pathway:194138] Signaling by VEGF - v50:[updateContainedPathway] [UpdateTracker:9776657] Update Tracker - [Pathway:194138] Signaling by VEGF - v74:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9846672] Update Tracker - [Pathway:194138] Signaling by VEGF - v84:[updateIndirectRLE] [UpdateTracker:9776032] Update Tracker - [Pathway:194138] Signaling by VEGF - v78:[updateIndirectRLE] [UpdateTracker:9780331] Update Tracker - [Pathway:194138] Signaling by VEGF - v63:[updateIndirectRLE] [UpdateTracker:9789319] Update Tracker - [Pathway:194138] Signaling by VEGF - v38:[updateContainedPathway] [UpdateTracker:9864294] Update Tracker - [Pathway:194138] Signaling by VEGF - v88:[updateIndirectRLE] [UpdateTracker:9782184] Update Tracker - [Pathway:194138] Signaling by VEGF - v59:[updateIndirectRLE] [UpdateTracker:9779142] Update Tracker - [Pathway:194138] Signaling by VEGF - v66:[modifyText, updateContainedPathway, updateIndirectRLE] [UpdateTracker:9780606] Update Tracker - [Pathway:194138] Signaling by VEGF - v62:[updateContainedPathway, updateIndirectRLE]

Referrals

(hasEvent)	[Pathway:R-HSA-9006934] Signaling by Receptor Tyrosine Kinases
(hasEncapsulatedEvent)	[Pathway:R-HSA-5668599] RHO GTPases Activate NADPH Oxidases [Pathway:R-HSA-9833482] PKR-mediated signaling
(updatedInstance)	[UpdateTracker:9782019] Update Tracker - [Pathway:194138] Signaling by VEGF - v60:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9784555] Update Tracker - [Pathway:194138] Signaling by VEGF - v53:[updateContainedPathway] [UpdateTracker:9784982] Update Tracker - [Pathway:194138] Signaling by VEGF - v52:[updateIndirectRLE] [UpdateTracker:9783107] Update Tracker - [Pathway:194138] Signaling by VEGF - v57:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9777129] Update Tracker - [Pathway:194138] Signaling by VEGF - v72:[addHasEvent] [UpdateTracker:9786599] Update Tracker - [Pathway:194138] Signaling by VEGF - v49:[addHasEvent, updateContainedPathway] [UpdateTracker:9778718] Update Tracker - [Pathway:194138] Signaling by VEGF - v67:[updateIndirectRLE] [UpdateTracker:9786225] Update Tracker - [Pathway:194138] Signaling by VEGF - v50:[updateContainedPathway] [UpdateTracker:9776657] Update Tracker - [Pathway:194138] Signaling by VEGF - v74:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9846672] Update Tracker - [Pathway:194138] Signaling by VEGF - v84:[updateIndirectRLE] [UpdateTracker:9776032] Update Tracker - [Pathway:194138] Signaling by VEGF - v78:[updateIndirectRLE] [UpdateTracker:9780331] Update Tracker - [Pathway:194138] Signaling by VEGF - v63:[updateIndirectRLE] [UpdateTracker:9789319] Update Tracker - [Pathway:194138] Signaling by VEGF - v38:[updateContainedPathway] [UpdateTracker:9864294] Update Tracker - [Pathway:194138] Signaling by VEGF - v88:[updateIndirectRLE] [UpdateTracker:9782184] Update Tracker - [Pathway:194138] Signaling by VEGF - v59:[updateIndirectRLE] [UpdateTracker:9779142] Update Tracker - [Pathway:194138] Signaling by VEGF - v66:[modifyText, updateContainedPathway, updateIndirectRLE] [UpdateTracker:9780606] Update Tracker - [Pathway:194138] Signaling by VEGF - v62:[updateContainedPathway, updateIndirectRLE]

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