Reactome | DT(33-225) [cytosol]

Schema > EntityWithAccessionedSequence > Entries

catalystActivities	[CatalystActivity:5336414] NAD+-diphthamide ADP-ribosyltransferase activity of DT(33-225) [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:5334087] D'Eustachio, Peter, 2014-02-21
crossReference	[DatabaseIdentifier:12020821] Mondo:0005504
dbId	5334080
disease	[Disease:5334089] diphtheria
displayName	DT(33-225) [cytosol]
endCoordinate	225
goCellularComponent	[GO_CellularComponent:2454709] host cell endocytic vesicle membrane
inDisease	true
literatureReference	[LiteratureReference:5334754] The amino acid sequence of fragment A, an enzymically active fragment of diphtheria toxin. III. The chymotryptic peptides, the peptides derived by cleavage at tryptophan residues, and the complete sequence of the protein [LiteratureReference:5339488] Partial characterization of diphtheria toxin and its subunits
maxDepth	1
modified	[InstanceEdit:9983308] Weiser, Joel, 2026-02-22
name	DT(33-225) Diphtheria toxin fragment A
producedByEvent	[BlackBoxEvent:R-HSA-5336420] DT fragment B transports DT fragment A from target cell endosome membrane - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:P00588] UniProt:P00588 Unknown
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:5333948] Corynephage beta
stId	R-CPH-5334080
startCoordinate	33

(output)	[BlackBoxEvent:R-HSA-5336420] DT fragment B transports DT fragment A from target cell endosome membrane
(physicalEntity)	[CatalystActivity:5336414] NAD+-diphthamide ADP-ribosyltransferase activity of DT(33-225) [cytosol]

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