Reactome | Expression of DDIT3

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Expression of DDIT3 Show undefined attributes

authored	[InstanceEdit:9635607] May, Bruce, 2019-02-06
category	omitted
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9635829] May, Bruce, 2019-02-09
dbId	9635841
displayName	Expression of DDIT3
edited	[InstanceEdit:9635607] May, Bruce, 2019-02-06
input	[EntityWithAccessionedSequence:R-CGR-9635853] DDIT3 gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:1791212] Two distinct stress signaling pathways converge upon the CHOP promoter during the mammalian unfolded protein response [LiteratureReference:9635827] DNA damage-inducible transcripts in mammalian cells [LiteratureReference:9635832] Signals from the stressed endoplasmic reticulum induce C/EBP-homologous protein (CHOP/GADD153)
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Expression of DDIT3
orthologousEvent	[BlackBoxEvent:R-HSA-9655071] Transcription of DDIT3 (CHOP, GADD153) in response to heme deficiency - Homo sapiens [BlackBoxEvent:R-HSA-1791107] Expression of DDIT3 (CHOP, GADD153) in response to unfolded protein - Homo sapiens [BlackBoxEvent:R-HSA-9644926] Transcription of DDIT3 (CHOP, GADD153) in response to amino acid deficiency - Homo sapiens
output	[EntityWithAccessionedSequence:R-CGR-9635849] DDIT3 [nucleoplasm]
regulatedBy	[PositiveGeneExpressionRegulation:9635788] Positive gene expression regulation by 'Atf4 dimer:DDIT3 gene [nucleoplasm]'
regulationReference	[RegulationReference:9641492] Positive gene expression regulation by 'Atf4 [nucleoplasm]' Two distinct stress signaling pathways converge upon the CHOP promoter during the mammalian unfolded protein response
releaseDate	2019-12-10
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9661246] Bruhat, Alain, 2019-09-15 [InstanceEdit:9664254] Chen, Jane-Jane, 2019-10-22 [InstanceEdit:9668172] Staschke, Kirk A, 2019-11-20
schemaClass	BlackBoxEvent
species	[Species:63514] Cricetulus griseus
stId	R-CGR-9635841
summation	[Summation:9635844] The DDIT3 (CHOP) gene is transcribed to yield mRNA and the m...