Reactome | RRAGC,D exchanges GTP for GDP

Schema > Reaction > Entries

RRAGC,D exchanges GTP for GDP Show undefined attributes

catalystActivity	[CatalystActivity:10194359] guanyl-nucleotide exchange factor activity of v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane]
category	transition
compartment	[Compartment:17938] lysosomal membrane
created	[InstanceEdit:10098795] Wright, Adam, 2024-03-07
dbId	10194361
displayName	RRAGC,D exchanges GTP for GDP
eventOf	[Pathway:R-CFA-9639288] Amino acids regulate mTORC1 - Canis familiaris
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-CFA-9640175] v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine - Canis familiaris
inferredFrom	[Reaction:R-HSA-9639286] RRAGC,D exchanges GTP for GDP - Homo sapiens
input	[SimpleEntity:R-ALL-29420] GDP [cytosol] [Complex:R-CFA-9640174] v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane]
isInDisease	false
isInferred	true
name	RRAGC,D exchanges GTP for GDP
output	[SimpleEntity:R-ALL-29438] GTP [cytosol] [Complex:R-CFA-9640184] v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane]
precedingEvent	[BlackBoxEvent:R-CFA-9639287] SESN1,2 binds L-leucine and dissociates from GATOR2 - Canis familiaris
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-9639286
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-9639288] Amino acids regulate mTORC1
(precedingEvent)	[Reaction:R-CFA-9640175] v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine
(inferredTo)	[Reaction:R-HSA-9639286] RRAGC,D exchanges GTP for GDP