Reactome | PIP3:BTK:G beta-gamma complex dissociates to Active BTK, PIP3 and G beta-gamma complex

Schema > Reaction > Entries

PIP3:BTK:G beta-gamma complex dissociates to Active BTK, PIP3 and G beta-gamma complex Show undefined attributes

category	dissociation
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10315021
displayName	PIP3:BTK:G beta-gamma complex dissociates to Active BTK, PIP3 and G beta-gamma complex
eventOf	[Pathway:R-CFA-8964315] G beta:gamma signalling through BTK - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8964317] PIP3:BTK:G beta-gamma complex dissociates to Active BTK, PIP3 and G beta-gamma complex - Homo sapiens
input	[Complex:R-CFA-8964249] PIP3:BTK:G-protein beta-gamma complex [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	PIP3:BTK:G beta-gamma complex dissociates to Active BTK, PIP3 and G beta-gamma complex
output	[EntityWithAccessionedSequence:R-CFA-197948] BTK [cytosol] [Complex:R-CFA-167434] G-protein beta-gamma complex [plasma membrane] [SimpleEntity:R-ALL-179838] PI(3,4,5)P3 [plasma membrane]
precedingEvent	[Reaction:R-CFA-8964271] BTK in PIP3:BTK:G beta-gamma complex is activated - Canis familiaris
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-8964317
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-8964315] G beta:gamma signalling through BTK
(inferredTo)	[Reaction:R-HSA-8964317] PIP3:BTK:G beta-gamma complex dissociates to Active BTK, PIP3 and G beta-gamma complex

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