Reactome | C2orf47:AFG3L2:SPG7:PHB:PHB2 [mitochondrial inner membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10313218] metalloendopeptidase activity of C2orf47:AFG3L2:SPG7:PHB:PHB2 [mitochondrial inner membrane]
compartment	[Compartment:70616] mitochondrial inner membrane
componentOf	[Complex:R-CFA-8949643] proSMDT1:C2orf47:AFG3L2:SPG7:PHB:PHB2 [mitochondrial inner membrane] - Canis familiaris
consumedByEvent	[Reaction:R-CFA-8949661] C2orf47:AFG3L2 binds the transit peptide of SMDT1 - Canis familiaris
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10313196
displayName	C2orf47:AFG3L2:SPG7:PHB:PHB2 [mitochondrial inner membrane]
hasComponent	[Complex:R-CFA-8949663] AFG3L2:Zn2+ [mitochondrial inner membrane] [EntityWithAccessionedSequence:R-CFA-8949660] MAIP1 [mitochondrial inner membrane] [Complex:R-CFA-8953727] PHB:PHB2 ring [mitochondrial inner membrane] [EntityWithAccessionedSequence:R-CFA-8953712] SPG7 [mitochondrial inner membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-8949645] C2orf47:AFG3L2:SPG7:PHB:PHB2 [mitochondrial inner membrane] - Homo sapiens
maxDepth	4
name	C2orf47:AFG3L2:SPG7:PHB:PHB2
producedByEvent	[Reaction:R-CFA-8949649] PMPCA:PMPCB cleaves the transit peptide of proSMDT1 (proEMRE) - Canis familiaris
schemaClass	Complex
species	[Species:49646] Canis familiaris
stId	R-CFA-8949645
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(physicalEntity)	[CatalystActivity:10313218] metalloendopeptidase activity of C2orf47:AFG3L2:SPG7:PHB:PHB2 [mitochondrial inner membrane]
(output)	[Reaction:R-CFA-8949649] PMPCA:PMPCB cleaves the transit peptide of proSMDT1 (proEMRE)
(input)	[Reaction:R-CFA-8949661] C2orf47:AFG3L2 binds the transit peptide of SMDT1
(hasComponent)	[Complex:R-CFA-8949643] proSMDT1:C2orf47:AFG3L2:SPG7:PHB:PHB2 [mitochondrial inner membrane]
(inferredTo)	[Complex:R-HSA-8949645] C2orf47:AFG3L2:SPG7:PHB:PHB2 [mitochondrial inner membrane]