Reactome | C2orf47:AFG3L2:SPG7:PHB:PHB2 [mitochondrial inner membrane]

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C2orf47:AFG3L2:SPG7:PHB:PHB2 [mitochondrial inner membrane] Show undefined attributes

catalystActivities	[CatalystActivity:8949658] metalloendopeptidase activity of C2orf47:AFG3L2:SPG7:PHB:PHB2 [mitochondrial inner membrane]
compartment	[Compartment:70616] mitochondrial inner membrane
componentOf	[Complex:R-HSA-8949643] proSMDT1:C2orf47:AFG3L2:SPG7:PHB:PHB2 [mitochondrial inner membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-8949661] C2orf47:AFG3L2 binds the transit peptide of SMDT1 - Homo sapiens
created	[InstanceEdit:8949656] May, Bruce, 2016-11-28
dbId	8949645
displayName	C2orf47:AFG3L2:SPG7:PHB:PHB2 [mitochondrial inner membrane]
hasComponent	[Complex:R-HSA-8949663] AFG3L2:Zn2+ [mitochondrial inner membrane] [EntityWithAccessionedSequence:R-HSA-8949660] C2orf47 [mitochondrial inner membrane] [Complex:R-HSA-8953727] PHB:PHB2 ring [mitochondrial inner membrane] [EntityWithAccessionedSequence:R-HSA-8953712] SPG7 [mitochondrial inner membrane]
inDisease	false
inferredTo	[Complex:R-MMU-8949645] C2orf47:AFG3L2:SPG7:PHB:PHB2 [mitochondrial inner membrane] - Mus musculus [Complex:R-RNO-8949645] C2orf47:AFG3L2:SPG7:PHB:PHB2 [mitochondrial inner membrane] - Rattus norvegicus [Complex:R-CFA-8949645] C2orf47:AFG3L2:SPG7:PHB:PHB2 [mitochondrial inner membrane] - Canis familiaris [Complex:R-BTA-8949645] C2orf47:AFG3L2:SPG7:PHB:PHB2 [mitochondrial inner membrane] - Bos taurus [Complex:R-SSC-8949645] C2orf47:AFG3L2:SPG7:PHB:PHB2 [mitochondrial inner membrane] - Sus scrofa [Complex:R-DRE-8949645] C2orf47:AFG3L2:SPG7:PHB:PHB2 [mitochondrial inner membrane] - Danio rerio [Complex:R-XTR-8949645] C2orf47:AFG3L2:SPG7:PHB:PHB2 [mitochondrial inner membrane] - Xenopus tropicalis [Complex:R-GGA-8949645] C2orf47:AFG3L2:SPG7:PHB:PHB2 [mitochondrial inner membrane] - Gallus gallus [Complex:R-DME-8949645] C2orf47:AFG3L2:SPG7:PHB:PHB2 [mitochondrial inner membrane] - Drosophila melanogaster [Complex:R-CEL-8949645] C2orf47:AFG3L2:SPG7:PHB:PHB2 [mitochondrial inner membrane] - Caenorhabditis elegans [Complex:R-DDI-8949645] C2orf47:AFG3L2:SPG7:PHB:PHB2 [mitochondrial inner membrane] - Dictyostelium discoideum [Complex:R-SPO-8949645] C2orf47:AFG3L2:SPG7:PHB:PHB2 [mitochondrial inner membrane] - Schizosaccharomyces pombe [Complex:R-SCE-8949645] C2orf47:AFG3L2:SPG7:PHB:PHB2 [mitochondrial inner membrane] - Saccharomyces cerevisiae [Complex:R-PFA-8949645] C2orf47:AFG3L2:SPG7:PHB:PHB2 [mitochondrial inner membrane] - Plasmodium falciparum
isChimeric	false
maxDepth	4
modified	[InstanceEdit:8956354] May, Bruce, 2017-01-22
name	C2orf47:AFG3L2:SPG7:PHB:PHB2 MAIP1:m-AAA Protease:Paraplegin:Prohibitin
producedByEvent	[Reaction:R-HSA-8949649] PMPCA:PMPCB cleaves the transit peptide of proSMDT1 (proEMRE) - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-8949645

Referrals

(physicalEntity)	[CatalystActivity:8949658] metalloendopeptidase activity of C2orf47:AFG3L2:SPG7:PHB:PHB2 [mitochondrial inner membrane]
(input)	[Reaction:R-HSA-8949661] C2orf47:AFG3L2 binds the transit peptide of SMDT1
(output)	[Reaction:R-HSA-8949649] PMPCA:PMPCB cleaves the transit peptide of proSMDT1 (proEMRE)
(hasComponent)	[Complex:R-HSA-8949643] proSMDT1:C2orf47:AFG3L2:SPG7:PHB:PHB2 [mitochondrial inner membrane]

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