Reactome | Translocation of STAT1 dimer to nucleus

Schema > BlackBoxEvent > Entries

Translocation of STAT1 dimer to nucleus Show undefined attributes

category	omitted
compartment	[Compartment:13231] nuclear envelope
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10260660
displayName	Translocation of STAT1 dimer to nucleus
eventOf	[Pathway:R-CFA-877300] Interferon gamma signaling - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CFA-997326] Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP - Canis familiaris [Reaction:R-CFA-877281] PIAS1 binds p-STAT1 dimer - Canis familiaris
inferredFrom	[BlackBoxEvent:R-HSA-873917] Translocation of STAT1 dimer to nucleus - Homo sapiens
input	[Complex:R-CFA-873827] IFNG-activated factor (GAF) [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Translocation of STAT1 dimer to nucleus
output	[Complex:R-CFA-873824] p-STAT1 homodimer [nucleoplasm]
precedingEvent	[Reaction:R-CFA-873927] Release of STAT1 dimer from active receptor unit - Canis familiaris
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:49646] Canis familiaris
stId	R-CFA-873917
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-877300] Interferon gamma signaling
(precedingEvent)	[Reaction:R-CFA-997326] Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP [Reaction:R-CFA-877281] PIAS1 binds p-STAT1 dimer
(inferredTo)	[BlackBoxEvent:R-HSA-873917] Translocation of STAT1 dimer to nucleus

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