Reactome | PCNA homotrimer [nucleoplasm]

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PCNA homotrimer [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-CFA-5655467] PCNA:RPA:RFC:Damaged DNA Template [nucleoplasm] - Canis familiaris [Complex:R-CFA-5358633] EXO1:MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch and single strand incision [nucleoplasm] - Canis familiaris [Complex:R-CFA-5358511] MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch [nucleoplasm] - Canis familiaris [Complex:R-CFA-174431] Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] - Canis familiaris
consumedByEvent	[Reaction:R-CFA-5358510] MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA - Canis familiaris [Reaction:R-CFA-6791109] GADD45A binds PCNA - Canis familiaris [Reaction:R-CFA-69063] Loading of PCNA - Sliding Clamp Formation - Canis familiaris [Reaction:R-CFA-174439] Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere - Canis familiaris
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10227037
displayName	PCNA homotrimer [nucleoplasm]
hasComponent	3 × [EntityWithAccessionedSequence:R-CFA-68439] PCNA [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-68440] PCNA homotrimer [nucleoplasm] - Homo sapiens
maxDepth	2
memberOf	[DefinedSet:R-CFA-6790532] PCNA homotrimer,MonoUb:K164-PCNA homotrimer [nucleoplasm] - Canis familiaris
name	PCNA homotrimer
producedByEvent	[Reaction:R-CFA-176702] Disassociation of Processive Complex and Completed Telomere End - Canis familiaris
schemaClass	Complex
species	[Species:49646] Canis familiaris
stId	R-CFA-68440
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(hasComponent)	[Complex:R-CFA-5655467] PCNA:RPA:RFC:Damaged DNA Template [nucleoplasm] [Complex:R-CFA-5653782] PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] [Complex:R-CFA-5358633] EXO1:MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch and single strand incision [nucleoplasm] [Complex:R-CFA-5358528] MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch and single strand incision [nucleoplasm] [Complex:R-CFA-5358511] MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch [nucleoplasm] [Complex:R-CFA-6790531] PCNA:POLD,POLE [nucleoplasm] [Complex:R-CFA-6791115] GADD45A:PCNA [nucleoplasm] [Complex:R-CFA-68471] RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] [Complex:R-CFA-68441] RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] [Complex:R-CFA-174449] RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end duplex:PCNA homotrimer [nucleoplasm] [Complex:R-CFA-174450] RNA primer-DNA primer:G-strand extended telomere:PCNA [nucleoplasm] [Complex:R-CFA-174435] Processive complex loaded on telomere:Okazaki fragment complex [nucleoplasm] [Complex:R-CFA-174431] Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] [Complex:R-CFA-174440] Processive complex loaded on telomere:Okazaki fragments:Remaining Flap [nucleoplasm] [Complex:R-CFA-174432] Processive complex loaded on telomere:nicked DNA from adjacent Okazaki fragments [nucleoplasm] [Complex:R-CFA-176394] Processive complex loaded on telomere:ligated C-strand Okazaki fragments [nucleoplasm] [Complex:R-CFA-5651799] PCNA:POLD,POLE:RPA:RFC [nucleoplasm]
(input)	[Reaction:R-CFA-5358510] MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA [Reaction:R-CFA-6791109] GADD45A binds PCNA [Reaction:R-CFA-69063] Loading of PCNA - Sliding Clamp Formation [Reaction:R-CFA-174439] Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere
(hasMember)	[DefinedSet:R-CFA-6790532] PCNA homotrimer,MonoUb:K164-PCNA homotrimer [nucleoplasm]
(output)	[Reaction:R-CFA-176702] Disassociation of Processive Complex and Completed Telomere End
(inferredTo)	[Complex:R-HSA-68440] PCNA homotrimer [nucleoplasm]

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