Reactome | MRE11 [nucleoplasm]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-CFA-75164] MRN [nucleoplasm] - Canis familiaris [Complex:R-CFA-75161] RAD50:MRE11A [nucleoplasm] - Canis familiaris
consumedByEvent	[Reaction:R-CFA-75172] Formation of RAD50:MRE11 complex - Canis familiaris
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10227410
displayName	MRE11 [nucleoplasm]
endCoordinate	708
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-59544] MRE11A [nucleoplasm] - Homo sapiens
maxDepth	1
name	MRE11 MRE11A A0A8I3P7Y4
referenceEntity	[ReferenceGeneProduct:uniprot:A0A8I3P7Y4] UniProt:A0A8I3P7Y4
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:49646] Canis familiaris
stId	R-CFA-59544
startCoordinate	1

(activeUnit)	[CatalystActivity:10296662] DNA endonuclease activity of DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-BRCA1-C complex [nucleoplasm]
(hasComponent)	[Complex:R-CFA-75164] MRN [nucleoplasm] [Complex:R-CFA-75161] RAD50:MRE11A [nucleoplasm] [Complex:R-CFA-5682166] p-MRN [nucleoplasm]
(input)	[Reaction:R-CFA-75172] Formation of RAD50:MRE11 complex
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-59544] MRE11A [nucleoplasm]

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