Reactome | p-MRN [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-CFA-5686620] DNA DSB with annealed 3' ssDNA overhangs and displaced flaps:p-MRN [nucleoplasm] - Canis familiaris [Complex:R-CFA-5685658] D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] - Canis familiaris [Complex:R-CFA-9980018] p-RPA:SSB-dsDNA with inter-SSA deletion:Flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex [nucleoplasm] - Canis familiaris
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10227421
displayName	p-MRN [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-CFA-59544] MRE11 [nucleoplasm] [EntityWithAccessionedSequence:R-CFA-75237] phospho-NBN [nucleoplasm] [EntityWithAccessionedSequence:R-CFA-75160] RAD50 [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-5682166] p-MRN [nucleoplasm] - Homo sapiens
maxDepth	2
name	p-MRN
producedByEvent	[BlackBoxEvent:R-CFA-5686663] Completion of SSA - Canis familiaris
schemaClass	Complex
species	[Species:49646] Canis familiaris
stId	R-CFA-5682166
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(output)	[BlackBoxEvent:R-CFA-5686663] Completion of SSA
(hasComponent)	[Complex:R-CFA-9980018] p-RPA:SSB-dsDNA with inter-SSA deletion:Flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex [nucleoplasm] [Complex:R-CFA-5686620] DNA DSB with annealed 3' ssDNA overhangs and displaced flaps:p-MRN [nucleoplasm] [Complex:R-CFA-5685986] 3' short overhanging ssDNA-DSBs:p-MRN [nucleoplasm] [Complex:R-CFA-5686226] Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] [Complex:R-CFA-5686487] Cleaved Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] [Complex:R-CFA-5685658] D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] [Complex:R-CFA-5686227] Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] [Complex:R-CFA-5686428] Cleaved D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] [Complex:R-CFA-5682175] DNA DSBs:p-MRN [nucleoplasm] [Complex:R-CFA-5684116] 3' overhanging ssDNA-DSBs:p-MRN [nucleoplasm]
(inferredTo)	[Complex:R-HSA-5682166] p-MRN [nucleoplasm]

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