Reactome | TFIIH binds GG-NER site to form a verification complex

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TFIIH binds GG-NER site to form a verification complex Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10296152
displayName	TFIIH binds GG-NER site to form a verification complex
eventOf	[Pathway:R-CFA-5696395] Formation of Incision Complex in GG-NER - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:17148] nucleotide-excision repair, preincision complex assembly
inferredFrom	[Reaction:R-HSA-5691000] TFIIH binds GG-NER site to form a verification complex - Homo sapiens
input	[Complex:R-CFA-109634] TFIIH [nucleoplasm] [Complex:R-CFA-5696681] Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	TFIIH binds GG-NER site to form a verification complex
output	[Complex:R-CFA-5689862] Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH:PAR-PARP1,PAR-PARP2 [nucleoplasm]
precedingEvent	[Reaction:R-CFA-5696655] PARP1 or PARP2 PARylates DDB2 and autoPARylates - Canis familiaris
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-5691000
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-5696395] Formation of Incision Complex in GG-NER
(inferredTo)	[Reaction:R-HSA-5691000] TFIIH binds GG-NER site to form a verification complex

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