Reactome | Formation of Incision Complex in GG-NER

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Formation of Incision Complex in GG-NER Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10329013
displayName	Formation of Incision Complex in GG-NER
eventOf	[Pathway:R-CFA-5696399] Global Genome Nucleotide Excision Repair (GG-NER) - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Pathway:R-CFA-5696400] Dual Incision in GG-NER - Canis familiaris
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-CFA-5691000] TFIIH binds GG-NER site to form a verification complex - Canis familiaris [Reaction:R-CFA-5696670] CHD1L is recruited to GG-NER site - Canis familiaris [Reaction:R-CFA-5690996] ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA - Canis familiaris [Reaction:R-CFA-6790487] RNF111 ubiquitinates SUMOylated XPC - Canis familiaris [Reaction:R-CFA-5689317] Formation of the pre-incision complex in GG-NER - Canis familiaris [Reaction:R-CFA-109955] Formation of ERCC1:XPF heterodimeric complex - Canis familiaris [Reaction:R-CFA-5690991] Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER - Canis familiaris
inferredFrom	[Pathway:R-HSA-5696395] Formation of Incision Complex in GG-NER - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Formation of Incision Complex in GG-NER
precedingEvent	[Pathway:R-CFA-5696394] DNA Damage Recognition in GG-NER - Canis familiaris
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49646] Canis familiaris
stId	R-CFA-5696395
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-5696399] Global Genome Nucleotide Excision Repair (GG-NER)
(precedingEvent)	[Pathway:R-CFA-5696400] Dual Incision in GG-NER
(inferredTo)	[Pathway:R-HSA-5696395] Formation of Incision Complex in GG-NER