Reactome | PRC1.4 complex binds H3K27Me3 nucleosomes on CDKN2A promoter

Schema > Reaction > Entries

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10281984
displayName	PRC1.4 complex binds H3K27Me3 nucleosomes on CDKN2A promoter
eventOf	[Pathway:R-CFA-2559580] Oxidative Stress Induced Senescence - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-3229089] PRC1.4 complex binds H3K27Me3 nucleosomes on CDKN2A promoter - Homo sapiens
input	[Complex:R-CFA-3222570] CDKN2A Gene:H3K27Me3-Nucleosome [nucleoplasm] [Complex:R-CFA-3229073] PRC1.4 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	PRC1.4 complex binds H3K27Me3 nucleosomes on CDKN2A promoter
output	[Complex:R-CFA-3229098] CDKN2A Gene:H3K27Me3-Nucleosome:PRC1.4 [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-3229089
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-CFA-2559580] Oxidative Stress Induced Senescence
(inferredTo)	[Reaction:R-HSA-3229089] PRC1.4 complex binds H3K27Me3 nucleosomes on CDKN2A promoter

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